Multiple proteolytic systems, including the proteasome, contribute to CFTR processing.
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Molecular Chaperones as Targets to Circumvent the CFTR Defect in Cystic FibrosisHook2 contributes to aggresome formationStress-associated endoplasmic reticulum protein 1 (SERP1)/Ribosome-associated membrane protein 4 (RAMP4) stabilizes membrane proteins during stress and facilitates subsequent glycosylationThe tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulumAdrenoleukodystrophy: subcellular localization and degradation of adrenoleukodystrophy protein (ALDP/ABCD1) with naturally occurring missense mutationsThe yeast split-ubiquitin membrane protein two-hybrid screen identifies BAP31 as a regulator of the turnover of endoplasmic reticulum-associated protein tyrosine phosphatase-like BE3 ubiquitin ligase COP1 regulates the stability and functions of MTA1Molecular cloning of the cDNA and chromosome localization of the gene for human ubiquitin-conjugating enzyme 9RNF185 is a novel E3 ligase of endoplasmic reticulum-associated degradation (ERAD) that targets cystic fibrosis transmembrane conductance regulator (CFTR)The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteinsRegulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination.Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasomeThe Hdj-2/Hsc70 chaperone pair facilitates early steps in CFTR biogenesisSubpopulations of proteasomes in rat liver nuclei, microsomes and cytosolThe human DnaJ homologue (Hdj)-1/heat-shock protein (Hsp) 40 co-chaperone is required for the in vivo stabilization of the cystic fibrosis transmembrane conductance regulator by Hsp70Effects of Anaplasma phagocytophila on NADPH oxidase components in human neutrophils and HL-60 cells.The cochaperone HspBP1 inhibits the CHIP ubiquitin ligase and stimulates the maturation of the cystic fibrosis transmembrane conductance regulatorType 2 iodothyronine deiodinase in rat pituitary tumor cells is inactivated in proteasomesDefective cellular trafficking of missense NPR-B mutants is the major mechanism underlying acromesomelic dysplasia-type MaroteauxOne step at a time: endoplasmic reticulum-associated degradationThe PEST sequence does not contribute to the stability of the cystic fibrosis transmembrane conductance regulatorA molecular portrait of the response to unfolded proteinsThe delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiologyIn vivo action of the HRD ubiquitin ligase complex: mechanisms of endoplasmic reticulum quality control and sterol regulation.Previously unknown role for the ubiquitin ligase Ubr1 in endoplasmic reticulum-associated protein degradation.Defining the glycan destruction signal for endoplasmic reticulum-associated degradationMembrane topology and function of Der3/Hrd1p as a ubiquitin-protein ligase (E3) involved in endoplasmic reticulum degradation.Der3p/Hrd1p is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins.Traffic-independent function of the Sar1p/COPII machinery in proteasomal sorting of the cystic fibrosis transmembrane conductance regulatorDistinct roles for the Hsp40 and Hsp90 molecular chaperones during cystic fibrosis transmembrane conductance regulator degradation in yeast.Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein.Degradation of subunits of the Sec61p complex, an integral component of the ER membrane, by the ubiquitin-proteasome pathway.CFTR Modulators: Shedding Light on Precision Medicine for Cystic FibrosisModulation of mature cystic fibrosis transmembrane regulator protein by the PDZ domain protein CALE3 ubiquitin ligase that recognizes sugar chainsCleaning up in the endoplasmic reticulum: ubiquitin in chargeCalnexin and other factors that alter translocation affect the rapid binding of ubiquitin to apoB in the Sec61 complexDegradation of the apical sodium-dependent bile acid transporter by the ubiquitin-proteasome pathway in cholangiocytesInclusion body myopathy-associated mutations in p97/VCP impair endoplasmic reticulum-associated degradationAggresomes: a cellular response to misfolded proteins
P2860
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P2860
Multiple proteolytic systems, including the proteasome, contribute to CFTR processing.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh-hant
name
Multiple proteolytic systems, including the proteasome, contribute to CFTR processing.
@en
Multiple proteolytic systems, including the proteasome, contribute to CFTR processing.
@nl
type
label
Multiple proteolytic systems, including the proteasome, contribute to CFTR processing.
@en
Multiple proteolytic systems, including the proteasome, contribute to CFTR processing.
@nl
prefLabel
Multiple proteolytic systems, including the proteasome, contribute to CFTR processing.
@en
Multiple proteolytic systems, including the proteasome, contribute to CFTR processing.
@nl
P2093
P1433
P1476
Multiple proteolytic systems, including the proteasome, contribute to CFTR processing.
@en
P2093
P304
P356
10.1016/0092-8674(95)90241-4
P407
P577
1995-10-01T00:00:00Z