about
OPA1 mutations induce mitochondrial DNA instability and optic atrophy 'plus' phenotypesWhy mitochondria must fuse to maintain their genome integritySphingosine-1-phosphate activates phospholipase D in human airway epithelial cells via a G protein-coupled receptorSyndromic parkinsonism and dementia associated with OPA1 missense mutationsThe background of mitochondrial DNA haplogroup J increases the sensitivity of Leber's hereditary optic neuropathy cells to 2,5-hexanedione toxicityProtection against oxidant-induced apoptosis by exogenous glutathione in Leber hereditary optic neuropathy cybrids.pH difference across the outer mitochondrial membrane measured with a green fluorescent protein mutant.The effects of idebenone on mitochondrial bioenergeticsDisruptive mitochondrial DNA mutations in complex I subunits are markers of oncocytic phenotype in thyroid tumors.An inherited mitochondrial DNA disruptive mutation shifts to homoplasmy in oncocytic tumor cells.Bioenergetics shapes cellular death pathways in Leber's hereditary optic neuropathy: a model of mitochondrial neurodegeneration.The cytochrome b p.278Y>C mutation causative of a multisystem disorder enhances superoxide production and alters supramolecular interactions of respiratory chain complexes.Gamma rays induce a p53-independent mitochondrial biogenesis that is counter-regulated by HIF1α.Learning from oncocytic tumors: Why choose inefficient mitochondria?Phospholipase D1 is threonine-phosphorylated in human-airway epithelial cells stimulated by sphingosine-1-phosphate by a mechanism involving Src tyrosine kinase and protein kinase Cdelta.Mitochondria: Biogenesis and mitophagy balance in segregation and clonal expansion of mitochondrial DNA mutations.Different mtDNA mutations modify tumor progression in dependence of the degree of respiratory complex I impairment.A mutation threshold distinguishes the antitumorigenic effects of the mitochondrial gene MTND1, an oncojanus function.Respiratory complex I dysfunction due to mitochondrial DNA mutations shifts the voltage threshold for opening of the permeability transition pore toward resting levels.The antioxidant function of Bcl-2 preserves cytoskeletal stability of cells with defective respiratory complex I.Glucose transport activation in human hematopoietic cells M07e is modulated by cytosolic calcium and calmodulin.Staurosporine induces apoptotic volume decrease (AVD) in ECV304 cells.7-Ketocholesterol and staurosporine induce opposite changes in intracellular pH, associated with distinct types of cell death in ECV304 cells.Phospholipase D stimulation is required for sphingosine-1-phosphate activation of actin stress fibre assembly in human airway epithelial cells.Arachidonic acid release by ionomycin and phorbol ester is similar in C127 epithelial cells expressing wild-type or mutated (delta F508) cystic fibrosis transmembrane conductance regulator.Role of CFTR and anion exchanger in bicarbonate fluxes in C127 cell lines.Characterization of chloride transport pathways in cultured human keratinocytes.'Behr syndrome' with OPA1 compound heterozygote mutations.The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization.Leber's hereditary optic neuropathy (LHON) pathogenic mutations induce mitochondrial-dependent apoptotic death in transmitochondrial cells incubated with galactose medium.Apoptotic cell death of cybrid cells bearing Leber's hereditary optic neuropathy mutations is caspase independent.Increased chloride efflux in fibroblasts from X-linked muscular dystrophies and clones from Duchenne carriers.Caspase-independent death of Leber's hereditary optic neuropathy cybrids is driven by energetic failure and mediated by AIF and Endonuclease G.OPA1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion.Rare mtDNA variants in Leber hereditary optic neuropathy families with recurrence of myoclonus.Studies on the transport of carnitine in the brain using synaptosomes isolated from guinea-pig cerebral cortex.A novel in-frame 18-bp microdeletion in MT-CYB causes a multisystem disorder with prominent exercise intolerance.A clinically complex form of dominant optic atrophy (OPA8) maps on chromosome 16.Green tea modulates alpha(1)-adrenergic stimulated glucose transport in cultured rat cardiomyocytes.Kinetic analysis of chloride efflux from normal and cystic fibrosis fibroblasts.
P50
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P50
description
hulumtuese
@sq
researcher
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wetenschapper
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հետազոտող
@hy
name
Michela Rugolo
@ast
Michela Rugolo
@en
Michela Rugolo
@es
Michela Rugolo
@nl
Michela Rugolo
@sl
type
label
Michela Rugolo
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Michela Rugolo
@en
Michela Rugolo
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Michela Rugolo
@nl
Michela Rugolo
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prefLabel
Michela Rugolo
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Michela Rugolo
@en
Michela Rugolo
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Michela Rugolo
@nl
Michela Rugolo
@sl
P106
P1153
7004596466
P21
P31
P496
0000-0002-4597-0452