Treg cell function in rheumatoid arthritis is compromised by ctla-4 promoter methylation resulting in a failure to activate the indoleamine 2,3-dioxygenase pathway.
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Towards an understanding of the role of DNA methylation in rheumatoid arthritis: therapeutic and diagnostic implicationsIDO2 in Immunomodulation and Autoimmune DiseaseThe thymus and rheumatology: should we care?Abatacept decreases disease activity in a absence of CD4(+) T cells in a collagen-induced arthritis model.The Proportion of Regulatory T Cells in Patients with Rheumatoid Arthritis: A Meta-AnalysisFecal metabolomics in pediatric spondyloarthritis implicate decreased metabolic diversity and altered tryptophan metabolism as pathogenic factors.Phenotypic, Functional, and Gene Expression Profiling of Peripheral CD45RA+ and CD45RO+ CD4+CD25+CD127(low) Treg Cells in Patients With Chronic Rheumatoid ArthritisDevelopment of a Functional Biomarker for Use in Cell-Based Therapy Studies in Seropositive Rheumatoid ArthritisCo-stimulatory and Co-inhibitory Pathways in Autoimmunity.Rheumatoid arthritis-associated RBPJ polymorphism alters memory CD4+ T cellsIDO1 and TGF-β Mediate Protective Effects of IFN-α in Antigen-Induced Arthritis.Therapeutics to block autoantibody initiation and propagation in systemic lupus erythematosus and rheumatoid arthritis.Altered immunoregulation in rheumatoid arthritis: the role of regulatory T cells and proinflammatory Th17 cells and therapeutic implications.Emerging aspects of molecular biomarkers for diagnosis, prognosis and treatment response in rheumatoid arthritis.Epigenetic drug discovery: breaking through the immune barrier.Epigenetics in the pathogenesis of RA.The role of interleukin-6 signalling and its therapeutic blockage in skewing the T cell balance in rheumatoid arthritis.Anti-TNF drives regulatory T cell expansion by paradoxically promoting membrane TNF-TNF-RII binding in rheumatoid arthritis.Genome-wide profiling in treatment-naive early rheumatoid arthritis reveals DNA methylome changes in T and B lymphocytes.Involvement of the IL-23/IL-17 axis and the Th17/Treg balance in the pathogenesis and control of autoimmune arthritis.A novel immunohistochemical score to predict early mortality in acute myeloid leukemia patients based on indoleamine 2,3 dioxygenase expression.L161982 alleviates collagen-induced arthritis in mice by increasing Treg cells and down-regulating Interleukin-17 and monocyte-chemoattractant protein-1 levels.CTLA-4 expressed by FOXP3+ regulatory T cells prevents inflammatory tissue attack and not T-cell priming in arthritis.In vitro Treg expansion favors the full-length splicing isoform of CTLA4.Interplay between genetic and epigenetic mechanisms in rheumatoid arthritis.Immune cells from patients with psoriasis are defective in inducing indoleamine 2,3-dioxygenase expression in response to inflammatory stimuli.DNA methylation as a marker of response in rheumatoid arthritis.Activation of the Regulatory T-Cell/Indoleamine 2,3-Dioxygenase Axis Reduces Vascular Inflammation and Atherosclerosis in Hyperlipidemic Mice.
P2860
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P2860
Treg cell function in rheumatoid arthritis is compromised by ctla-4 promoter methylation resulting in a failure to activate the indoleamine 2,3-dioxygenase pathway.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
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name
Treg cell function in rheumato ...... amine 2,3-dioxygenase pathway.
@en
Treg cell function in rheumato ...... amine 2,3-dioxygenase pathway.
@nl
type
label
Treg cell function in rheumato ...... amine 2,3-dioxygenase pathway.
@en
Treg cell function in rheumato ...... amine 2,3-dioxygenase pathway.
@nl
prefLabel
Treg cell function in rheumato ...... amine 2,3-dioxygenase pathway.
@en
Treg cell function in rheumato ...... amine 2,3-dioxygenase pathway.
@nl
P2093
P2860
P356
P1476
Treg cell function in rheumato ...... eamine 2,3-dioxygenase pathway
@en
P2093
Bernard Gregory
Fionula M Brennan
Henry Penn
Jordan E Read
Khaja Syed
Parisa Amjadi
Patricia Green
Richard O Williams
Szymon W Manka
P2860
P304
P356
10.1002/ART.38715
P577
2014-09-01T00:00:00Z