Sulforaphane prevents the development of cardiomyopathy in type 2 diabetic mice probably by reversing oxidative stress-induced inhibition of LKB1/AMPK pathway.
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An Overview of Murine High Fat Diet as a Model for Type 2 Diabetes MellitusThe Role of p38 MAPK in the Development of Diabetic CardiomyopathyDietary Phytochemicals: Natural Swords Combating Inflammation and Oxidation-Mediated Degenerative DiseasesExtracts of Magnolia Species-Induced Prevention of Diabetic Complications: A Brief ReviewDiabetic Microvascular Disease and Pulmonary Fibrosis: The Contribution of Platelets and Systemic InflammationSulforaphane Protects against Cardiovascular Disease via Nrf2 ActivationMolecular and Cellular Mechanisms of Cardiovascular Disorders in DiabetesZinc rescues obesity-induced cardiac hypertrophy via stimulating metallothionein to suppress oxidative stress-activated BCL10/CARD9/p38 MAPK pathway.Modulation of Metabolic Detoxification Pathways Using Foods and Food-Derived Components: A Scientific Review with Clinical ApplicationAnabolic and Antiresorptive Modulation of Bone Homeostasis by the Epigenetic Modulator Sulforaphane, a Naturally Occurring Isothiocyanate.Repurposing the NRF2 Activator Dimethyl Fumarate as Therapy Against Synucleinopathy in Parkinson's DiseaseBroccoli sprout extract prevents diabetic cardiomyopathy via Nrf2 activation in db/db T2DM miceZinc Prevents the Development of Diabetic Cardiomyopathy in db/db Mice.Protective role of sulphoraphane against vascular complications in diabetes.Sulforaphane Protects against High Cholesterol-Induced Mitochondrial Bioenergetics Impairments, Inflammation, and Oxidative Stress and Preserves Pancreatic β-Cells Function.AMPK in Cardiovascular Diseases.4-hydroxynonenal-mediated signaling and aging.Nrf2 targeting by sulforaphane: A potential therapy for cancer treatment.Inhibition of STAT3 phosphorylation by sulforaphane reduces adhesion molecule expression in vascular endothelial cell.Cardioprotective effects of fibroblast growth factor 21 against doxorubicin-induced toxicity via the SIRT1/LKB1/AMPK pathway.Protective effects of curcumin on acute gentamicin-induced nephrotoxicity in rats.Effect of curcumin on glycerol-induced acute kidney injury in rats.Targeting Mitochondrial Dysfunction for the Treatment of Diabetic Complications: Pharmacological Interventions through Natural ProductsOxidative stress and inflammation as central mediators of atrial fibrillation in obesity and diabetesNuclear factor (erythroid derived 2)-like 2 activation increases exercise endurance capacity via redox modulation in skeletal muscles.Beneficial Role of Some Natural Products to Attenuate the Diabetic Cardiomyopathy Through Nrf2 Pathway in Cell Culture and Animal Models.Role of tissue transglutaminase in the pathogenesis of diabetic cardiomyopathy and the intervention effect of rutin.Zinc delays the progression of obesity-related glomerulopathy in mice via down-regulating P38 MAPK-mediated inflammation.Regulation of Sirtuin-Mediated Protein Deacetylation by Cardioprotective Phytochemicals.Antioxidative Effects of Natural Products on Diabetic Cardiomyopathy.Activation of Nrf2 signaling by natural products-can it alleviate diabetes?Metallothionein Is Downstream of Nrf2 and Partially Mediates Sulforaphane Prevention of Diabetic Cardiomyopathy.Endothelial Cell Metabolism.Inhibition of p53 prevents diabetic cardiomyopathy by preventing early-stage apoptosis and cell senescence, reduced glycolysis, and impaired angiogenesis.Fibroblast growth factor-21 prevents diabetic cardiomyopathy via AMPK-mediated antioxidation and lipid-lowering effects in the heart.Decreased carboxylesterases expression and hydrolytic activity in type 2 diabetic mice through Akt/mTOR/HIF-1α/Stra13 pathway.Recent novel approaches to limit oxidative stress and inflammation in diabetic complications.An Intervention Target for Myocardial Fibrosis: Autophagy.Mechanistic insights into the augmented effect of bone marrow mesenchymal stem cells and thiazolidinediones in streptozotocin-nicotinamide induced diabetic rats.Diabetic Cardiomyopathy: Current and Future Therapies. Beyond Glycemic Control
P2860
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P2860
Sulforaphane prevents the development of cardiomyopathy in type 2 diabetic mice probably by reversing oxidative stress-induced inhibition of LKB1/AMPK pathway.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh-hant
name
Sulforaphane prevents the deve ...... hibition of LKB1/AMPK pathway.
@en
Sulforaphane prevents the deve ...... hibition of LKB1/AMPK pathway.
@nl
type
label
Sulforaphane prevents the deve ...... hibition of LKB1/AMPK pathway.
@en
Sulforaphane prevents the deve ...... hibition of LKB1/AMPK pathway.
@nl
prefLabel
Sulforaphane prevents the deve ...... hibition of LKB1/AMPK pathway.
@en
Sulforaphane prevents the deve ...... hibition of LKB1/AMPK pathway.
@nl
P2093
P1476
Sulforaphane prevents the deve ...... hibition of LKB1/AMPK pathway.
@en
P2093
Junlian Gu
Maiying Kong
Nicholas Mellen
Shanshan Zhou
Shudong Wang
Xiaoqing Yan
Yang Zheng
P356
10.1016/J.YJMCC.2014.09.022
P577
2014-09-28T00:00:00Z