Silencing of RB1 but not of RB2/P130 induces cellular senescence and impairs the differentiation potential of human mesenchymal stem cells.
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Senescence in Human Mesenchymal Stem Cells: Functional Changes and Implications in Stem Cell-Based TherapyRadio-resistant mesenchymal stem cells: mechanisms of resistance and potential implications for the clinicRB maintains quiescence and prevents premature senescence through upregulation of DNMT1 in mesenchymal stromal cells.Proof of principle: quality control of therapeutic cell preparations using senescence-associated DNA-methylation changes.Radiation-induced alterations of osteogenic and chondrogenic differentiation of human mesenchymal stem cells.MiR-101 induces senescence and prevents apoptosis in the background of DNA damage in MCF7 cells.De-regulated expression of the BRG1 chromatin remodeling factor in bone marrow mesenchymal stromal cells induces senescence associated with the silencing of NANOG and changes in the levels of chromatin proteinsIdentity, proliferation capacity, genomic stability and novel senescence markers of mesenchymal stem cells isolated from low volume of human bone marrow.Lessons learned about human stem cell responses to ionizing radiation exposures: a long road still ahead of us.p107-Dependent recruitment of SWI/SNF to the alkaline phosphatase promoter during osteoblast differentiation.Silencing of RB1 and RB2/P130 during adipogenesis of bone marrow stromal cells results in dysregulated differentiation.Senescence bypass in mesenchymal stem cells: a potential pathogenesis and implications of pro-senescence therapy in sarcomas.The gap between the physiological and therapeutic roles of mesenchymal stem cells.Senescence suppressors: their practical importance in replicative lifespan extension in stem cells.Myeloma cells can corrupt senescent mesenchymal stromal cells and impair their anti-tumor activity.Impact of lysosomal storage disorders on biology of mesenchymal stem cells: Evidences from in vitro silencing of glucocerebrosidase (GBA) and alpha-galactosidase A (GLA) enzymes.Balancing Between Aging and Cancer: Molecular Genetics Meets Traditional Chinese Medicine.Molecular connections of obesity and aging: a focus on adipose protein 53 and retinoblastoma protein.Co-Activation of PKC-δ by CRIF1 Modulates Oxidative Stress in Bone Marrow Multipotent Mesenchymal Stromal Cells after Irradiation by Phosphorylating NRF2 Ser40.Long-term changes in the properties of skin-derived fibroblasts following irradiation of the head and neck.Mesenchymal stromal cells having inactivated RB1 survive following low irradiation and accumulate damaged DNA: Hints for side effects following radiotherapy.Insulin-like growth factor binding proteins 4 and 7 released by senescent cells promote premature senescence in mesenchymal stem cellsAdipose-Derived Mesenchymal Stem Cells from the Elderly Exhibit Decreased Migration and Differentiation Abilities with Senescent Properties.Irradiation of Mesenchymal Stromal Cells With Low and High Doses of Alpha Particles Induces Senescence and/or Apoptosis.Human mesenchymal stem cells lose their functional properties after paclitaxel treatment.Isolation, characterization and cardiac differentiation of human thymus tissue derived mesenchymal stromal cells.RB orchestrates fat cell and cell fate.The replicative senescent mesenchymal stem / stromal cells defect in DNA damage response and anti-oxidative capacity.Hybrid complexes of high and low molecular weight hyaluronan delay in vitro replicative senescence of mesenchymal stromal cells: a pilot study for future therapeutic application
P2860
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P2860
Silencing of RB1 but not of RB2/P130 induces cellular senescence and impairs the differentiation potential of human mesenchymal stem cells.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh-hant
name
Silencing of RB1 but not of RB ...... human mesenchymal stem cells.
@en
Silencing of RB1 but not of RB ...... human mesenchymal stem cells.
@nl
type
label
Silencing of RB1 but not of RB ...... human mesenchymal stem cells.
@en
Silencing of RB1 but not of RB ...... human mesenchymal stem cells.
@nl
prefLabel
Silencing of RB1 but not of RB ...... human mesenchymal stem cells.
@en
Silencing of RB1 but not of RB ...... human mesenchymal stem cells.
@nl
P2093
P2860
P50
P1476
Silencing of RB1 but not of RB ...... human mesenchymal stem cells.
@en
P2093
Flavio Rizzolio
Johannes Beckers
Verena Rauchberger
Wolfgang Bohn
P2860
P2888
P304
P356
10.1007/S00018-012-1224-X
P577
2013-01-31T00:00:00Z