The role of the GX9GX3G motif in the gating of high voltage-activated Ca2+ channels.
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Loss of Ca(v)1.3 (CACNA1D) function in a human channelopathy with bradycardia and congenital deafnessTowards a Unified Theory of Calmodulin Regulation (Calmodulation) of Voltage-Gated Calcium and Sodium ChannelsThe role of distal S6 hydrophobic residues in the voltage-dependent gating of CaV2.3 channels.Functional characterization of CaVα2δ mutations associated with sudden cardiac deathCooperative activation of the T-type CaV3.2 channel: interaction between Domains II and III.Characterization of the gating brake in the I-II loop of CaV3 T-type calcium channels.Ins and outs of T-channel structure function.Molecular endpoints of Ca2+/calmodulin- and voltage-dependent inactivation of Ca(v)1.3 channelsDouble mutant cycle analysis identified a critical leucine residue in the IIS4S5 linker for the activation of the Ca(V)2.3 calcium channel.Arrhythmogenesis in Timothy Syndrome is associated with defects in Ca(2+)-dependent inactivationThe Timothy syndrome mutation differentially affects voltage- and calcium-dependent inactivation of CaV1.2 L-type calcium channels.An autism-associated mutation in CaV1.3 channels has opposing effects on voltage- and Ca(2+)-dependent regulation.Disruption of the IS6-AID linker affects voltage-gated calcium channel inactivation and facilitation.L-type Ca2+ channel function during Timothy syndromeTimothy mutation disrupts the link between activation and inactivation in Ca(V)1.2 protein.Determination of the Relative Cell Surface and Total Expression of Recombinant Ion Channels Using Flow Cytometry.Different pathways for activation and deactivation in CaV1.2: a minimal gating modelThe Timothy syndrome mutation of cardiac CaV1.2 (L-type) channels: multiple altered gating mechanisms and pharmacological restoration of inactivation.Physicochemical properties of pore residues predict activation gating of Ca V1.2: a correlation mutation analysis.Ca(V)1.2 I-II linker structure and Timothy syndrome.Interaction of the S6 proline hinge with N-type and C-type inactivation in Kv1.4 channels.Calmodulin mutations associated with long QT syndrome prevent inactivation of cardiac L-type Ca(2+) currents and promote proarrhythmic behavior in ventricular myocytes.Neutralisation of a single voltage sensor affects gating determinants in all four pore-forming S6 segments of Ca(V)1.2: a cooperative gating model.Molecular determinants of the CaVbeta-induced plasma membrane targeting of the CaV1.2 channel.Coupled and independent contributions of residues in IS6 and IIS6 to activation gating of CaV1.2.Topology of the selectivity filter of a TRPV channel: rapid accessibility of contiguous residues from the external medium.Inherited Ventricular Arrhythmias: The Role of the Multi-Subunit Structure of the L-Type Calcium Channel Complex.Mutations in voltage-gated L-type calcium channel: implications in cardiac arrhythmia
P2860
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P2860
The role of the GX9GX3G motif in the gating of high voltage-activated Ca2+ channels.
description
2006 nî lūn-bûn
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
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2006年學術文章
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name
The role of the GX9GX3G motif in the gating of high voltage-activated Ca2+ channels.
@en
The role of the GX9GX3G motif in the gating of high voltage-activated Ca2+ channels.
@nl
type
label
The role of the GX9GX3G motif in the gating of high voltage-activated Ca2+ channels.
@en
The role of the GX9GX3G motif in the gating of high voltage-activated Ca2+ channels.
@nl
prefLabel
The role of the GX9GX3G motif in the gating of high voltage-activated Ca2+ channels.
@en
The role of the GX9GX3G motif in the gating of high voltage-activated Ca2+ channels.
@nl
P2093
P2860
P356
P1476
The role of the GX9GX3G motif in the gating of high voltage-activated Ca2+ channels.
@en
P2093
Alexandra Raybaud
Daniel G Bichet
Lucie Parent
Manuel Simoes
Pierre Bissonnette
Rémy Sauvé
Yolaine Dodier
P2860
P304
39424-39436
P356
10.1074/JBC.M607405200
P407
P577
2006-10-11T00:00:00Z