Soluble adenylyl cyclase (sAC) is indispensable for sperm function and fertilization.
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Somatic 'soluble' adenylyl cyclase isoforms are unaffected in Sacy tm1Lex/Sacy tm1Lex 'knockout' miceRole of the bicarbonate-responsive soluble adenylyl cyclase in pH sensing and metabolic regulationPhysiology of na+/h+ exchangers in the male reproductive tract: relevance for male fertilityThe role of soluble adenylyl cyclase in neurite outgrowthIntracellular cAMP signaling by soluble adenylyl cyclase.K+ and Cl- channels and transporters in sperm functionΔ9-Tetrahydrocannabinol (Δ9-THC) attenuates mouse sperm motility and male fecundityA polycystin-1 controls postcopulatory reproductive selection in miceParticipation of the Cl-/HCO(3)- exchangers SLC26A3 and SLC26A6, the Cl- channel CFTR, and the regulatory factor SLC9A3R1 in mouse sperm capacitationSodium-hydrogen exchanger NHA1 and NHA2 control sperm motility and male fertilityInhibition of human sperm motility by contraceptive anti-eppin antibodies from infertile male monkeys: effect on cyclic adenosine monophosphateCyclic 3',5'-AMP causes ADAM1/ADAM2 to rapidly diffuse within the plasma membrane of guinea pig spermPharmacological targeting of native CatSper channels reveals a required role in maintenance of sperm hyperactivation.Glycolysis and mitochondrial respiration in mouse LDHC-null spermBicarbonate-sensing soluble adenylyl cyclase is an essential sensor for acid/base homeostasisRoles of the oviduct in mammalian fertilization.A host defense mechanism involving CFTR-mediated bicarbonate secretion in bacterial prostatitis.Ion channels, phosphorylation and mammalian sperm capacitation.The CatSper channel: a polymodal chemosensor in human spermCytokine-induced iNOS and ERK1/2 inhibit adenylyl cyclase type 5/6 activity and stimulate phosphodiesterase 4D5 activity in intestinal longitudinal smooth muscle.Testicular expression of Adora3i2 in Adora3 knockout mice reveals a role of mouse A3Ri2 and human A3Ri3 adenosine receptors in spermPhysiological carbon dioxide, bicarbonate, and pH sensingSoluble adenylyl cyclase in health and disease.Central role of soluble adenylyl cyclase and cAMP in sperm physiology.Control of hyperactivation in sperm.Physiological sensing of carbon dioxide/bicarbonate/pH via cyclic nucleotide signaling.Controlling fertilization and cAMP signaling in sperm by optogenetics.Rediscovering sperm ion channels with the patch-clamp technique.Targeted disruption of glycogen synthase kinase 3A (GSK3A) in mice affects sperm motility resulting in male infertility.Wrath of the wraiths of CatSper3 and CatSper4.Heads or tails? Structural events and molecular mechanisms that promote mammalian sperm acrosomal exocytosis and motility.A sperm-specific Na+/H+ exchanger (sNHE) is critical for expression and in vivo bicarbonate regulation of the soluble adenylyl cyclase (sAC)Role of soluble adenylyl cyclase in the heart.Posttesticular sperm maturation, infertility, and hypercholesterolemia.What can we learn about fertilization from cystic fibrosis?Metabolic substrates exhibit differential effects on functional parameters of mouse sperm capacitationProtein-tyrosine kinase signaling in the biological functions associated with sperm.Normal Fertility Requires the Expression of Carbonic Anhydrases II and IV in Sperm.External Ca2+ acts upstream of adenylyl cyclase SACY in the bicarbonate signaled activation of sperm motility.Biphasic role of calcium in mouse sperm capacitation signaling pathways
P2860
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P2860
Soluble adenylyl cyclase (sAC) is indispensable for sperm function and fertilization.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Soluble adenylyl cyclase (sAC) is indispensable for sperm function and fertilization.
@en
type
label
Soluble adenylyl cyclase (sAC) is indispensable for sperm function and fertilization.
@en
prefLabel
Soluble adenylyl cyclase (sAC) is indispensable for sperm function and fertilization.
@en
P2093
P1476
Soluble adenylyl cyclase (sAC) is indispensable for sperm function and fertilization.
@en
P2093
Anne E Carlson
Bijay S Jaiswal
Gloria Esposito
Jan A Gossen
Manuel A Garcia
Marcel van Duin
Marco Conti
Sonya M Schuh
P304
P356
10.1016/J.YDBIO.2006.05.038
P407
P577
2006-06-07T00:00:00Z