Mechanisms of spindle-pole organization are influenced by kinetochore activity in mammalian cells.
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Identification of a TPX2-like microtubule-associated protein in DrosophilaCLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelityBuilding a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora ATPX2 regulates the localization and activity of Eg5 in the mammalian mitotic spindleThe kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells.KIFC1: a promising chemotherapy target for cancer treatment?The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cellsChromokinesin Kid and kinetochore kinesin CENP-E differentially support chromosome congression without end-on attachment to microtubulesStudies of haspin-depleted cells reveal that spindle-pole integrity in mitosis requires chromosome cohesionChromosome congression in the absence of kinetochore fibres.Bisphenol A directly targets tubulin to disrupt spindle organization in embryonic and somatic cells.Force on spindle microtubule minus ends moves chromosomesDynein light intermediate chains maintain spindle bipolarity by functioning in centriole cohesion.Abnormal kinetochore-generated pulling forces from expressing a N-terminally modified Hec1.CENP-W plays a role in maintaining bipolar spindle structure.Aurora-A inactivation causes mitotic spindle pole fragmentation by unbalancing microtubule-generated forcesStructural and regulatory roles of nonmotor spindle proteinsSynchronizing chromosome segregation by flux-dependent force equalization at kinetochores.Kif2a regulates spindle organization and cell cycle progression in meiotic oocytes.Function and regulation of dynein in mitotic chromosome segregation.Mitotic spindle multipolarity without centrosome amplification.The Elephant in the Room: The Role of Microtubules in Cancer.CLASPs prevent irreversible multipolarity by ensuring spindle-pole resistance to traction forces during chromosome alignment.Inhibiting Crm1 causes the formation of excess acentriolar spindle poles containing NuMA and B23, but does not affect centrosome numbers.Influence of centriole number on mitotic spindle length and symmetry.The pesticide dichlorvos disrupts mitotic division by delocalizing the kinesin Kif2a from centrosomes.Regulators of Spindle Microtubules and Their Mechanisms: Living Together Matters.N-terminus-modified Hec1 suppresses tumour growth by interfering with kinetochore-microtubule dynamics.An inducible RNA interference system in Physcomitrella patens reveals a dominant role of augmin in phragmoplast microtubule generation
P2860
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P2860
Mechanisms of spindle-pole organization are influenced by kinetochore activity in mammalian cells.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Mechanisms of spindle-pole org ...... e activity in mammalian cells.
@en
Mechanisms of spindle-pole org ...... e activity in mammalian cells.
@nl
type
label
Mechanisms of spindle-pole org ...... e activity in mammalian cells.
@en
Mechanisms of spindle-pole org ...... e activity in mammalian cells.
@nl
prefLabel
Mechanisms of spindle-pole org ...... e activity in mammalian cells.
@en
Mechanisms of spindle-pole org ...... e activity in mammalian cells.
@nl
P1433
P1476
Mechanisms of spindle-pole org ...... e activity in mammalian cells.
@en
P2093
Amity L Manning
Duane A Compton
P304
P356
10.1016/J.CUB.2006.11.071
P407
P577
2007-02-01T00:00:00Z