ADOA3R as a therapeutic target in experimental colitis: proof by validated high-density oligonucleotide microarray analysis. - Wikidata - wikimedia - TriplyDB

ADOA3R as a therapeutic target in experimental colitis: proof by validated high-density oligonucleotide microarray analysis.

ADOA3R as a therapeutic target in experimental colitis: proof by validated high-density oligonucleotide microarray analysis.

http://www.wikidata.org/entity/Q50718849

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Purinergic Signaling in Gut Inflammation: The Role of Connexins and Pannexins Purinergic signalling in the gastrointestinal tract and related organs in health and disease Potential for developing purinergic drugs for gastrointestinal diseases Recent developments in adenosine receptor ligands and their potential as novel drugs The anti-inflammatory effect of A3 adenosine receptor agonists: a novel targeted therapy for rheumatoid arthritis.Dual purinergic synaptic transmission in the human enteric nervous system.Synthesis and pharmacological characterization of [(125)I]MRS5127, a high affinity, selective agonist radioligand for the A3 adenosine receptor Purinergic autocrine regulation of mechanosensitivity and serotonin release in a human EC model: ATP-gated P2X3 channels in EC are downregulated in ulcerative colitis Contribution of adenosine A2B receptors to inflammatory parameters of experimental colitis Activation of adenosine low-affinity A3 receptors inhibits the enteric short interplexus neural circuit triggered by histamine.Targeting the A2B adenosine receptor during gastrointestinal ischemia and inflammation Feed-forward inhibition of CD73 and upregulation of adenosine deaminase contribute to the loss of adenosine neuromodulation in postinflammatory ileitis.Ion channel remodeling in gastrointestinal inflammation Functionalized congeners of A3 adenosine receptor-selective nucleosides containing a bicyclo[3.1.0]hexane ring system.Impact of disrupting adenosine A₃ receptors (A₃⁻/⁻ AR) on colonic motility or progression of colitis in the mouse.An adenosine A3 receptor agonist inhibits DSS-induced colitis in mice through modulation of the NF-κB signaling pathway.Opioid use affects antioxidant activity and purine metabolism: preliminary results.Neuropharmacology of purinergic receptors in human submucous plexus: Involvement of P2X₁, P2X₂, P2X₃ channels, P2Y and A₃ metabotropic receptors in neurotransmission Pharmacological and therapeutic effects of A3 adenosine receptor agonists Activation of neuronal P2X7 receptor-pannexin-1 mediates death of enteric neurons during colitis.Structure-guided design of A(3) adenosine receptor-selective nucleosides: combination of 2-arylethynyl and bicyclo[3.1.0]hexane substitutions.Introduction to adenosine receptors as therapeutic targets.Design of (N)-methanocarba adenosine 5'-uronamides as species-independent A3 receptor-selective agonists.Investigational A₃ adenosine receptor targeting agents.Purinergic receptors and gastrointestinal secretomotor function.Pharmacological modulation of adenosine system: novel options for treatment of inflammatory bowel diseases.Purinergic receptors and synaptic transmission in enteric neurons.The A3 adenosine receptor agonist CF502 inhibits the PI3K, PKB/Akt and NF-kappaB signaling pathway in synoviocytes from rheumatoid arthritis patients and in adjuvant-induced arthritis rats New bioinformatics approach to analyze gene expressions and signaling pathways reveals unique purine gene dysregulation profiles that distinguish between CD and UC.Synthesis and characterization of [76Br]-labeled high-affinity A3 adenosine receptor ligands for positron emission tomography.Novel 2- and 4-substituted 1H-imidazo[4,5-c]quinolin-4-amine derivatives as allosteric modulators of the A3 adenosine receptor MicroRNA-206 is involved in the pathogenesis of ulcerative colitis via regulation of adenosine A3 receptor.The A3 adenosine receptor as multifaceted therapeutic target: pharmacology, medicinal chemistry, and in silico approaches.Quality of methods reporting in animal models of colitis.Purinergic Signalling in the Gut.Activation of adenosine A3 receptor alleviates TNF-α-induced inflammation through inhibition of the NF-κB signaling pathway in human colonic epithelial cells.Oral Feeding of Probiotic Bifidobacterium infantis: Colonic Morphological Changes in Rat Model of TNBS-Induced Colitis.Molecular Signaling and Dysfunction of the Human Reactive Enteric Glial Cell Phenotype: Implications for GI Infection, IBD, POI, Neurological, Motility, and GI Disorders Control of enteric neuromuscular functions by purinergic A(3) receptors in normal rat distal colon and experimental bowel inflammation Overexpression of ATP-activated P2X7 receptors in the intestinal mucosa is implicated in the pathogenesis of Crohn's disease.

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P2860

ADOA3R as a therapeutic target in experimental colitis: proof by validated high-density oligonucleotide microarray analysis.

http://www.wikidata.org/entity/Q50718849

description

2006 nî lūn-bûn

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2006年の論文

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年学术文章

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2006年學術文章

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name

ADOA3R as a therapeutic target ...... ucleotide microarray analysis.

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ADOA3R as a therapeutic target ...... ucleotide microarray analysis.

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type

label

ADOA3R as a therapeutic target ...... ucleotide microarray analysis.

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ADOA3R as a therapeutic target ...... ucleotide microarray analysis.

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prefLabel

ADOA3R as a therapeutic target ...... ucleotide microarray analysis.

@en

ADOA3R as a therapeutic target ...... ucleotide microarray analysis.

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Inflammatory Bowel Diseases

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ADOA3R as a therapeutic target ...... ucleotide microarray analysis.

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Andrey Bozarov

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Arturo J Cardounel

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Asad Javed

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Fievos L Christofi

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Hamdy H Hassanain

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Helen Cooke

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Herbert Auer

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Iveta Grants

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Jacqueline E Wunderlich

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Jeff Palatini

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P2860

Differential gene expression of adenosine A1, A2a, A2b, and A3 receptors in the human enteric nervous system

Postoperative maintenance of Crohn's disease remission with 6-mercaptopurine, mesalamine, or placebo: a 2-year trial

Inhibition of inducible nitric oxide synthase in the human intestinal epithelial cell line, DLD-1, by the inducers of heme oxygenase 1, bismuth salts, heme, and nitric oxide donors

Involvement of benzodiazepine receptors in neuroinflammatory and neurodegenerative diseases: evidence from activated microglial cells in vitro

The molecular biology of memory storage: a dialogue between genes and synapses

Cloned adenosine A3 receptors: pharmacological properties, species differences and receptor functions.

Chemokine expression in IBD. Mucosal chemokine expression is unselectively increased in both ulcerative colitis and Crohn's disease.

Gene expression in papillary thyroid carcinoma reveals highly consistent profiles

Medicinal chemistry of adenosine A3 receptor ligands.

Oxidative mechanisms of hemoglobin-based blood substitutes.

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8

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