Clearance mechanism of a mannosylated antibody-enzyme fusion protein used in experimental cancer therapy.
about
High-mannose glycans on the Fc region of therapeutic IgG antibodies increase serum clearance in humans.Intracellular reprogramming of expression, glycosylation, and function of a plant-derived antiviral therapeutic monoclonal antibodyN-glycan PK Profiling Using a High Sensitivity nanoLCMS Work-Flow with Heavy Stable Isotope Labeled Internal Standard and Application to a Preclinical Study of an IgG1 Biopharmaceutical.Impact of expression system on the function of the C6.5 diabody PET radiotracerAntibody-enzyme fusion proteins for cancer therapy.Modulating antibody pharmacokinetics using hydrophilic polymers.Proposed mechanism of off-target toxicity for antibody-drug conjugates driven by mannose receptor uptake.Liver cell-targeted delivery of therapeutic molecules.Engineering novel Lec1 glycosylation mutants in CHO-DUKX cells: molecular insights and effector modulation of N-acetylglucosaminyltransferase I.Engineering the yeast Yarrowia lipolytica for the production of therapeutic proteins homogeneously glycosylated with Man₈GlcNAc₂ and Man₅GlcNAc₂.Highly parallel characterization of IgG Fc binding interactions.Development of Kupffer cell targeting type-I interferon for the treatment of hepatitis via inducing anti-inflammatory and immunomodulatory actions.
P2860
Q31004131-F9573BB4-9D2A-4381-85C4-C6FE619B621DQ34962237-E15989EE-3A84-477F-985F-076A81552934Q36133312-CA00F0F6-87F8-415F-AC96-23E6BAA1BA90Q37142836-C8EDFCDA-DA11-4A43-8844-D9723C20F22AQ37842324-A1C0ABAB-CF19-4DB6-B7A4-55C37D482C51Q37919888-1EB35EC2-A4AE-4E6C-BB58-CC45C28AC843Q38065955-00FF4264-D1AF-494C-AB8B-CA7DB5911580Q38229624-13113EF3-1386-4CE9-B8BA-5BFF2E04015CQ38328602-6E944632-1478-44C5-AF77-FA462FC81D18Q42380751-03E0A8F6-4C8D-42E2-94BA-BA0269D91FCAQ42909129-CBBFE920-4B09-45EC-A389-CEBBE76F11FCQ52567489-1FE5A27E-A8E0-4E63-A6C0-8E44A6766D87
P2860
Clearance mechanism of a mannosylated antibody-enzyme fusion protein used in experimental cancer therapy.
description
2006 nî lūn-bûn
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
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2006年學術文章
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2006年學術文章
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name
Clearance mechanism of a manno ...... n experimental cancer therapy.
@en
Clearance mechanism of a manno ...... n experimental cancer therapy.
@nl
type
label
Clearance mechanism of a manno ...... n experimental cancer therapy.
@en
Clearance mechanism of a manno ...... n experimental cancer therapy.
@nl
prefLabel
Clearance mechanism of a manno ...... n experimental cancer therapy.
@en
Clearance mechanism of a manno ...... n experimental cancer therapy.
@nl
P2093
P2860
P356
P1433
P1476
Clearance mechanism of a manno ...... n experimental cancer therapy.
@en
P2093
Berend Tolner
Heide Kogelberg
Kerry A Chester
Mark W Lowdell
Mathew Robson
R Barbara Pedley
Richard H J Begent
Roland Contreras
Surinder K Sharma
Tim Hillyer
P2860
P356
10.1093/GLYCOB/CWL053
P577
2006-09-25T00:00:00Z