Effector-memory T cells develop in islets and report islet pathology in type 1 diabetes.
about
Opposing effects of CTLA4 insufficiency on regulatory versus conventional T cells in autoimmunity converge on effector memory in target tissue.Antigen recognition in the islets changes with progression of autoimmune islet infiltration.Population dynamics of islet-infiltrating cells in autoimmune diabetes.Characterization of Diabetogenic CD8+ T Cells: IMMUNE THERAPY WITH METABOLIC BLOCKADE.Perinatal tolerance to proinsulin is sufficient to prevent autoimmune diabetes.Perforin facilitates beta cell killing and regulates autoreactive CD8+ T-cell responses to antigen in mouse models of type 1 diabetes.Type I Interferon Is a Catastrophic Feature of the Diabetic Islet MicroenvironmentPeripheral blood mononuclear cells of patients with latent autoimmune diabetes secrete higher levels of pro- & anti-inflammatory cytokines compared to those with type-1 diabetes mellitus following in vitro stimulation with β-cell autoantigens.CD137 Plays Both Pathogenic and Protective Roles in Type 1 Diabetes Development in NOD Mice.
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P2860
Effector-memory T cells develop in islets and report islet pathology in type 1 diabetes.
description
2013 nî lūn-bûn
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name
Effector-memory T cells develop in islets and report islet pathology in type 1 diabetes.
@en
Effector-memory T cells develop in islets and report islet pathology in type 1 diabetes.
@nl
type
label
Effector-memory T cells develop in islets and report islet pathology in type 1 diabetes.
@en
Effector-memory T cells develop in islets and report islet pathology in type 1 diabetes.
@nl
prefLabel
Effector-memory T cells develop in islets and report islet pathology in type 1 diabetes.
@en
Effector-memory T cells develop in islets and report islet pathology in type 1 diabetes.
@nl
P2093
P50
P356
P1476
Effector-memory T cells develop in islets and report islet pathology in type 1 diabetes.
@en
P2093
Ania Skowera
Balasubramanian Krishnamurthy
Gaurang Jhala
Helen E Thomas
Hyun-Ja Ko
Kate L Graham
Robyn M Sutherland
Tara Catterall
Thomas W H Kay
P304
P356
10.4049/JIMMUNOL.1302100
P407
P577
2013-12-11T00:00:00Z