Selectivity and Kinetic Requirements of HDAC Inhibitors as Progranulin Enhancers for Treating Frontotemporal Dementia.

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Epigenetic Targeting of Granulin in Hepatoma Cells by Synthetic CRISPR dCas9 Epi-suppressors.

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Selectivity and Kinetic Requirements of HDAC Inhibitors as Progranulin Enhancers for Treating Frontotemporal Dementia.

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Selectivity and Kinetic Requir ...... ating Frontotemporal Dementia.

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Selectivity and Kinetic Requir ...... ating Frontotemporal Dementia.

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Selectivity and Kinetic Requir ...... ating Frontotemporal Dementia.

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Selectivity and Kinetic Requir ...... ating Frontotemporal Dementia.

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Selectivity and Kinetic Requir ...... ating Frontotemporal Dementia.

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Selectivity and Kinetic Requir ...... ating Frontotemporal Dementia.

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Selectivity and Kinetic Requir ...... ating Frontotemporal Dementia.

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Angela She

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Audrey Lang

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Bradford C Dickerson

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Iren Kurtser

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Jenny Lai

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Joachim Herz

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Krista Hennig

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Ralph Mazitschek

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Stephen J Haggarty

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Surya A Reis

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Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes

The human genome browser at UCSC

Mechanisms of granulin deficiency: lessons from cellular and animal models

Histone Deacetylase (HDAC) Inhibitor Kinetic Rate Constants Correlate with Cellular Histone Acetylation but Not Transcription and Cell Viability

Selective class IIa histone deacetylase inhibition via a nonchelating zinc-binding group

Kinetic and structural insights into the binding of histone deacetylase 1 and 2 (HDAC1, 2) inhibitors

The Human Epigenome Browser at Washington University

ENCODE data in the UCSC Genome Browser: year 5 update

A selective HDAC 1/2 inhibitor modulates chromatin and gene expression in brain and alters mouse behavior in two mood-related tests

Light-controlled modulation of gene expression by chemical optoepigenetic probes

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892-906.e5

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scholarly article

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10.1016/J.CHEMBIOL.2017.06.010

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Ralph Mazitschek

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2017-07-11T00:00:00Z

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28712747

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Selectivity and Kinetic Requirements of HDAC Inhibitors as Progranulin Enhancers for Treating Frontotemporal Dementia.

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Selectivity and Kinetic Requirements of HDAC Inhibitors as Progranulin Enhancers for Treating Frontotemporal Dementia.

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