Mouse Noxa uses only the C-terminal BH3-domain to inactivate Mcl-1.
about
In contrast to Chlamydia trachomatis, Waddlia chondrophila grows in human cells without inhibiting apoptosis, fragmenting the Golgi apparatus, or diverting post-Golgi sphingomyelin transportThe copper chelator ATN-224 induces caspase-independent cell death in diffuse large B cell lymphomaThe functional differences between pro-survival and pro-apoptotic B cell lymphoma 2 (Bcl-2) proteins depend on structural differences in their Bcl-2 homology 3 (BH3) domains.The carboxyl-terminal tail of Noxa protein regulates the stability of Noxa and Mcl-1The pro-apoptotic BH3-only protein Bim interacts with components of the translocase of the outer mitochondrial membrane (TOM)Infection of epithelial cells with Chlamydia trachomatis inhibits TNF-induced apoptosis at the level of receptor internalization while leaving non-apoptotic TNF-signalling intact.Dynein light chain 1 induces assembly of large Bim complexes on mitochondria that stabilize Mcl-1 and regulate apoptosis.
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Q27322698-D6522E30-9C76-4BC0-869D-F110EFDF7BC9Q28389285-AB5F0234-3CEB-486A-ACBF-E9E4549C2311Q30368405-6C209B3E-3978-4CB0-AE73-EE4089FF78E0Q33793022-044E93AF-40B1-42F3-9535-9B5B6E551CA9Q35602342-79973882-66A5-4C93-977D-63C4FF64325CQ37835512-1C372D09-2E4E-48A5-A467-B8864374D785Q47690517-47CADE2B-9138-4725-9573-5DFD00B41760
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Mouse Noxa uses only the C-terminal BH3-domain to inactivate Mcl-1.
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name
Mouse Noxa uses only the C-terminal BH3-domain to inactivate Mcl-1.
@en
Mouse Noxa uses only the C-terminal BH3-domain to inactivate Mcl-1.
@nl
type
label
Mouse Noxa uses only the C-terminal BH3-domain to inactivate Mcl-1.
@en
Mouse Noxa uses only the C-terminal BH3-domain to inactivate Mcl-1.
@nl
prefLabel
Mouse Noxa uses only the C-terminal BH3-domain to inactivate Mcl-1.
@en
Mouse Noxa uses only the C-terminal BH3-domain to inactivate Mcl-1.
@nl
P2093
P2860
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P1476
Mouse Noxa uses only the C-terminal BH3-domain to inactivate Mcl-1.
@en
P2093
Arnim Weber
David Ausländer
Georg Häcker
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P2888
P304
P356
10.1007/S10495-013-0868-9
P577
2013-09-01T00:00:00Z