Osteopontin signaling upregulates cyclooxygenase-2 expression in tumor-associated macrophages leading to enhanced angiogenesis and melanoma growth via α9β1 integrin.
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Pro-Tumoral Inflammatory Myeloid Cells as Emerging Therapeutic TargetsOsteopontin promotes aromatase expression and estradiol production in human adipocytesExogenous IGFBP-2 promotes proliferation, invasion, and chemoresistance to temozolomide in glioma cells via the integrin β1-ERK pathwayOsteopontin Deficiency Suppresses Intestinal Tumor Development in Apc-Deficient Min MiceChanges in the transcriptional profile in response to overexpression of the osteopontin-c splice isoform in ovarian (OvCar-3) and prostate (PC-3) cancer cell lines.OPN induces FoxM1 expression and localization through ERK 1/2, AKT, and p38 signaling pathway in HEC-1A cells.The significance of the co-existence of osteopontin and tumor-associated macrophages in gastric cancer progressionOsteopontin promotes a cancer stem cell-like phenotype in hepatocellular carcinoma cells via an integrin-NF-κB-HIF-1α pathwayDeep-proteome mapping of WM-266-4 human metastatic melanoma cells: From oncogenic addiction to druggable targetsOsteopontin-integrin interaction as a novel molecular target for antibody-mediated immunotherapy in adult T-cell leukemia.Insulin-like growth factor-independent insulin-like growth factor binding protein 3 promotes cell migration and lymph node metastasis of oral squamous cell carcinoma cells by requirement of integrin β1.The effect of celecoxib on tumor growth in ovarian cancer cells and a genetically engineered mouse model of serous ovarian cancer.The role of tumor-associated macrophages in tumor vascularization.Activin promotes skin carcinogenesis by attraction and reprogramming of macrophages.Therapeutic implications of cellular and molecular biology of cancer stem cells in melanoma.Role of osteopontin in the pathophysiology of cancer.Osteopontin as a therapeutic target for cancer.Osteopontin -- a promising biomarker for cancer therapy.Osteopontin: its potential role in cancer of children and young adults.Cellular metabolism of tumor-associated macrophages - functional impact and consequences.Osteopontin at the Crossroads of Inflammation and Tumor Progression.Type 2 diabetes alters mesenchymal stem cell secretome composition and angiogenic properties.Hairy/enhancer of Split Homologue-1 Suppresses Vascular Endothelial Growth Factor-induced Angiogenesis via Downregulation of Osteopontin Expression.Beyond adhesion: emerging roles for integrins in control of the tumor microenvironment.Pericyte Seeded Dual Peptide Scaffold with Improved Endothelialization for Vascular Graft Tissue Engineering.Osteopontin production by TM4SF4 signaling drives a positive feedback autocrine loop with the STAT3 pathway to maintain cancer stem cell-like properties in lung cancer cells.Epoxyazadiradione suppresses breast tumor growth through mitochondrial depolarization and caspase-dependent apoptosis by targeting PI3K/Akt pathway.Unfavorable effect of calcitriol and its low-calcemic analogs on metastasis of 4T1 mouse mammary gland cancer.Relationship of Cx43 regulation of vascular permeability to osteopontin-tight junction protein pathway after sepsis in rats.Tumor-Associated Macrophages: Therapeutic Targets for Skin Cancer.Cancer-associated Fibroblast-derived IL-6 Promotes Head and Neck Cancer Progression via the Osteopontin-NF-kappa B Signaling Pathway.An exploratory study investigating the metabolic activity and local cytokine profile in patients with melanoma treated with pazopanib and paclitaxel.Intranasal Delivery of RGD Motif-Containing Osteopontin Icosamer Confers Neuroprotection in the Postischemic Brain via αvβ3 Integrin Binding.Macrophages in skin melanoma-the key element in melanomagenesis.Doxorubicin Hydrochloride Loaded Zymosan-Polyethylenimine Biopolymeric Nanoparticles for Dual 'Chemoimmunotherapeutic' Intervention in Breast Cancer.Interleukin-18 Amplifies Macrophage Polarization and Morphological Alteration, Leading to Excessive Angiogenesis.[Advances in Research of Osteopontion and Its Receptor CD44v in Tumor Invasion and Metastasis].
P2860
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P2860
Osteopontin signaling upregulates cyclooxygenase-2 expression in tumor-associated macrophages leading to enhanced angiogenesis and melanoma growth via α9β1 integrin.
description
2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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name
Osteopontin signaling upregula ...... noma growth via α9β1 integrin.
@en
Osteopontin signaling upregula ...... noma growth via α9β1 integrin.
@nl
type
label
Osteopontin signaling upregula ...... noma growth via α9β1 integrin.
@en
Osteopontin signaling upregula ...... noma growth via α9β1 integrin.
@nl
prefLabel
Osteopontin signaling upregula ...... noma growth via α9β1 integrin.
@en
Osteopontin signaling upregula ...... noma growth via α9β1 integrin.
@nl
P2093
P2860
P356
P1433
P1476
Osteopontin signaling upregula ...... noma growth via α9β1 integrin.
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2013.184
P407
P50
P577
2013-06-03T00:00:00Z