Atypical, bidirectional regulation of cadmium-induced apoptosis via distinct signaling of unfolded protein response.
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CHAC1/MGC4504 is a novel proapoptotic component of the unfolded protein response, downstream of the ATF4-ATF3-CHOP cascadeExperimental Evidence Shows Salubrinal, an eIF2α Dephosphorylation Inhibitor, Reduces Xenotoxicant-Induced Cellular DamageEpigenetic effects of cadmium in cancer: focus on melanomaAberrant, differential and bidirectional regulation of the unfolded protein response towards cell survival by 3'-deoxyadenosinemTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1-JNK pathwayEndoplasmic reticulum stress and unfolded protein response in renal pathophysiology: Janus facesEndoplasmic reticulum stress plays a pivotal role in cell death mediated by the pan-deacetylase inhibitor panobinostat in human hepatocellular cancer cells.ER stress in retinal degeneration in S334ter Rho rats.Diverse pathways for maturation of the Na,K-ATPase β1 and β2 subunits in the endoplasmic reticulum of Madin-Darby canine kidney cells13-acetoxysarcocrassolide induces apoptosis on human gastric carcinoma cells through mitochondria-related apoptotic pathways: p38/JNK activation and PI3K/AKT suppressionDual regulation of cadmium-induced apoptosis by mTORC1 through selective induction of IRE1 branches in unfolded protein response.Connexin43 hemichannels contribute to cadmium-induced oxidative stress and cell injury.Molecular Cloning and mRNA Expression of Heat Shock Protein Genes and Their Response to Cadmium Stress in the Grasshopper Oxya chinensis.Hormetic effects of acute methylmercury exposure on grp78 expression in rat brain cortex.Tungsten Toxicity in PlantsControl of NF-κB and inflammation by the unfolded protein response.Implications of endoplasmic reticulum stress, the unfolded protein response and apoptosis for molecular cancer therapy. Part I: targeting p53, Mdm2, GADD153/CHOP, GRP78/BiP and heat shock proteins.The unfolded protein response triggered by environmental factors.Cadmium and cellular signaling cascades: interactions between cell death and survival pathways.Heavy metals and metalloids as a cause for protein misfolding and aggregation.Involvement of selective reactive oxygen species upstream of proapoptotic branches of unfolded protein response.Cadmium-induced ER stress and inflammation are mediated through C/EBP-DDIT3 signaling in human bronchial epithelial cells.Initial autophagic protection switches to disruption of autophagic flux by lysosomal instability during cadmium stress accrual in renal NRK-52E cells.LcBiP, a endoplasmic reticulum chaperone binding protein gene from Lycium chinense, confers cadmium tolerance in transgenic tobacco.Blocking autophagy enhances the apoptosis effect of bufalin on human hepatocellular carcinoma cells through endoplasmic reticulum stress and JNK activation.Heat shock proteins as key biological targets of the marine natural cyclopeptide perthamide C.Cadmium-induced autophagy in rat kidney: an early biomarker of subtoxic exposure.Cadmium impairs protein folding in the endoplasmic reticulum and induces the unfolded protein response.Acidic pH environments increase the expression of cathepsin B in osteoblasts: the significance of ER stress in bone physiology.Suppression of cytokine responses by indomethacin in podocytes: a mechanism through induction of unfolded protein response.Cadmium induces Wnt signaling to upregulate proliferation and survival genes in sub-confluent kidney proximal tubule cells.Glycolaldehyde induces endoplasmic reticulum stress and apoptosis in Schwann cellsLive and Let Die: Roles of Autophagy in Cadmium Nephrotoxicity.Ameliorative Effects of Selenium on Cadmium-Induced Oxidative Stress and Endoplasmic Reticulum Stress in the Chicken Kidney.Oral exposure of mice to cadmium (II), chromium (VI) and their mixture induce oxidative- and endoplasmic reticulum-stress mediated apoptosis in the livers.Crosstalk between endoplasmic reticulum stress and mitochondrial pathway mediates cadmium-induced germ cell apoptosis in testes.Effects of salubrinal on cadmium-induced apoptosis in HK-2 human renal proximal tubular cells.Dual suppression of adipogenesis by cigarette smoke through activation of the aryl hydrocarbon receptor and induction of endoplasmic reticulum stress.Selective deletion of adipocytes, but not preadipocytes, by TNF-alpha through C/EBP- and PPARgamma-mediated suppression of NF-kappaB.Effect of stachydrine on endoplasmic reticulum stress-induced apoptosis in rat kidney after unilateral ureteral obstruction.
P2860
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P2860
Atypical, bidirectional regulation of cadmium-induced apoptosis via distinct signaling of unfolded protein response.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Atypical, bidirectional regula ...... of unfolded protein response.
@en
Atypical, bidirectional regula ...... of unfolded protein response.
@nl
type
label
Atypical, bidirectional regula ...... of unfolded protein response.
@en
Atypical, bidirectional regula ...... of unfolded protein response.
@nl
prefLabel
Atypical, bidirectional regula ...... of unfolded protein response.
@en
Atypical, bidirectional regula ...... of unfolded protein response.
@nl
P2093
P2860
P356
P1476
Atypical, bidirectional regula ...... g of unfolded protein response
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.CDD.4402154
P577
2007-04-27T00:00:00Z