about
Subcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurological disordersOvergrowth Syndromes.Impact of NGS in the medical sciences: Genetic syndromes with an increased risk of developing cancer as an example of the use of new technologiesTherapeutic targeting of cancers with loss of PTEN function.New insights into POLE and POLD1 germline mutations in familial colorectal cancer and polyposisPro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling patA functional dissection of PTEN N-terminus: implications in PTEN subcellular targeting and tumor suppressor activityGenetic predisposition to colorectal cancer: where we stand and future perspectivesInhibition of mitotic Aurora kinase A by alisertib induces apoptosis and autophagy of human gastric cancer AGS and NCI-N78 cells.Esophageal cancer in a family with hamartomatous tumors and germline PTEN frameshift and SMAD7 missense mutations.A unified nomenclature and amino acid numbering for human PTEN.Autism spectrum disorder and epilepsy: Disorders with a shared biology.Epidermal growth factor receptor pathway mutation and expression profiles in cervical squamous cell carcinoma: therapeutic implications.Mutations in the PP2A regulatory subunit B family genes PPP2R5B, PPP2R5C and PPP2R5D cause human overgrowth.Autism Linked to Increased Oncogene Mutations but Decreased Cancer Rate.Alisertib Induces Cell Cycle Arrest, Apoptosis, Autophagy and Suppresses EMT in HT29 and Caco-2 Cells.FGFR and PTEN signaling interact during lens development to regulate cell survivalA recessive form of extreme macrocephaly and mild intellectual disability complements the spectrum of PTEN hamartoma tumour syndromeCapillary Isoelectric Focusing of Akt Isoforms Identifies Highly Dynamic Phosphorylation in Neuronal Cells and Brain TissueImmune dysregulation in patients with PTEN hamartoma tumor syndrome: Analysis of FOXP3 regulatory T cells.Induction of mitochondria-mediated apoptosis and PI3K/Akt/ mTOR-mediated autophagy by aflatoxin B2 in hepatocytes of broilersAlisertib induces G2/M arrest, apoptosis, and autophagy via PI3K/Akt/mTOR- and p38 MAPK-mediated pathways in human glioblastoma cellsThe Paradox of Akt-mTOR Interactions.Redox control of enzymatic functions: The electronics of life's circuitry.Hereditary colorectal cancer syndromes and genetic testing.Cowden syndrome: recognizing and managing a not-so-rare hereditary cancer syndrome.Using Genetics to Identify Hereditary Colorectal Polyposis and Cancer Syndromes in Your Patient.Approach to the Diagnosis of Overgrowth Syndromes.Breast cancer risk and clinical implications for germline PTEN mutation carriers.Somatic overgrowth disorders of the PI3K/AKT/mTOR pathway & therapeutic strategies.Mosaic Disorders of the PI3K/PTEN/AKT/TSC/mTORC1 Signaling Pathway.PTEN functions by recruitment to cytoplasmic vesicles.Molecular pathways: PI3K pathway phosphatases as biomarkers for cancer prognosis and therapyOleic acid induces apoptosis and autophagy in the treatment of Tongue Squamous cell carcinomas.A proteomics-based investigation on the anticancer activity of alisertib, an Aurora kinase A inhibitor, in hepatocellular carcinoma Hep3B cells.Danusertib, a potent pan-Aurora kinase and ABL kinase inhibitor, induces cell cycle arrest and programmed cell death and inhibits epithelial to mesenchymal transition involving the PI3K/Akt/mTOR-mediated signaling pathway in human gastric cancer AGSInduction of apoptosis and autophagy via mitochondria- and PI3K/Akt/mTOR-mediated pathways by E. adenophorum in hepatocytes of saanen goat.Induction of apoptosis and autophagy via sirtuin1- and PI3K/Akt/mTOR-mediated pathways by plumbagin in human prostate cancer cells.Quantitative Missense Variant Effect Prediction Using Large-Scale Mutagenesis Data.Euptox A Induces G1 Arrest and Autophagy via p38 MAPK- and PI3K/Akt/mTOR-Mediated Pathways in Mouse Splenocytes.
P2860
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P2860
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh-hant
name
When overgrowth bumps into cancer: the PTEN-opathies.
@en
When overgrowth bumps into cancer: the PTEN-opathies.
@nl
type
label
When overgrowth bumps into cancer: the PTEN-opathies.
@en
When overgrowth bumps into cancer: the PTEN-opathies.
@nl
prefLabel
When overgrowth bumps into cancer: the PTEN-opathies.
@en
When overgrowth bumps into cancer: the PTEN-opathies.
@nl
P2860
P356
P1476
When overgrowth bumps into cancer: the PTEN-opathies.
@en
P2093
Jessica Mester
P2860
P304
P356
10.1002/AJMG.C.31364
P50
P577
2013-05-01T00:00:00Z