about
Potent immunity to low doses of influenza vaccine by probabilistic guided micro-targeted skin delivery in a mouse modelThe changing shape of vaccination: improving immune responses through geometrical variations of a microdevice for immunizationInactivated poliovirus type 2 vaccine delivered to rat skin via high density microprojection array elicits potent neutralising antibody responses.Dry-coated live viral vector vaccines delivered by nanopatch microprojections retain long-term thermostability and induce transgene-specific T cell responses in miceNanopatch-targeted skin vaccination against West Nile Virus and Chikungunya virus in mice.Characterising the material properties at the interface between skin and a skin vaccination microprojection device.Allometric scaling of skin thickness, elasticity, viscoelasticity to mass for micro-medical device translation: from mice, rats, rabbits, pigs to humans.Formulations for microprojection/microneedle vaccine delivery: Structure, strength and release profiles.The hyperelastic and failure behaviors of skin in relation to the dynamic application of microscopic penetrators in a murine model.Surface-modified microprojection arrays for intradermal biomarker capture, with low non-specific protein binding.Microprojection arrays to immunise at mucosal surfaces.Improving the reach of vaccines to low-resource regions, with a needle-free vaccine delivery device and long-term thermostabilizationDry-coated microprojection array patches for targeted delivery of immunotherapeutics to the skinSensors for Fetal Hypoxia and Metabolic Acidosis: A ReviewTargeted epidermal delivery of vaccines from coated micro-nanoprojection patchesImproved DNA vaccination by skin-targeted delivery using dry-coated densely-packed microprojection arraysSpace- and time-resolved investigation on diffusion kinetics of human skin following macromolecule delivery by microneedle arraysTargeted, Needle-Free Vaccinations in Skin using Multilayered, Densely-Packed Dissolving Microprojection ArraysThe effect of strain rate on the precision of penetration of short densely-packed microprojection array patches coated with vaccineElastic modulus and viscoelastic properties of full thickness skin characterised at micro scalesThe viscoelastic, hyperelastic and scale dependent behaviour of freshly excised individual skin layersCellular metabolism and pore lifetime of human skin following microprojection array mediationImmune response and reactogenicity of an unadjuvanted intradermally delivered human papillomavirus vaccine using a first generation Nanopatch™ in rhesus macaques: An exploratory, pre-clinical feasibility assessmentA low inflammatory, Langerhans cell-targeted microprojection patch to deliver ovalbumin to the epidermis of mouse skin
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Michael L Crichton
@es
Michael L Crichton
@nl
Michael L Crichton
@sl
Michael L. Crichton
@en
type
label
Michael L Crichton
@es
Michael L Crichton
@nl
Michael L Crichton
@sl
Michael L. Crichton
@en
prefLabel
Michael L Crichton
@es
Michael L Crichton
@nl
Michael L Crichton
@sl
Michael L. Crichton
@en
P106
P1153
35309551800
P31
P496
0000-0002-3683-802X