Loss of p53 induces leukemic transformation in a murine model of Jak2 V617F-driven polycythemia vera.

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Low-burden TP53 mutations in chronic phase of myeloproliferative neoplasms: association with age, hydroxyurea administration, disease type and JAK2 mutational status.Oncogenic activation of the STAT3 pathway drives PD-L1 expression in natural killer/T-cell lymphoma

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Loss of p53 induces leukemic transformation in a murine model of Jak2 V617F-driven polycythemia vera.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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name

Loss of p53 induces leukemic t ...... 617F-driven polycythemia vera.

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Loss of p53 induces leukemic t ...... 617F-driven polycythemia vera.

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Loss of p53 induces leukemic t ...... 617F-driven polycythemia vera.

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Loss of p53 induces leukemic t ...... 617F-driven polycythemia vera.

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Loss of p53 induces leukemic t ...... 617F-driven polycythemia vera.

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Loss of p53 induces leukemic t ...... 617F-driven polycythemia vera.

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P1476

Loss of p53 induces leukemic t ...... 617F-driven polycythemia vera.

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P2093

H Kobayashi

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K Kataoka

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K Narukawa

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T Tsuruta-Kishino

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Y Sumitomo

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P2860

Pbx1 is a downstream target of Evi-1 in hematopoietic stem/progenitors and leukemic cells

Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2

A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis

Inducible gene targeting in mice

A gain-of-function mutation of JAK2 in myeloproliferative disorders

Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders

Long-term haematopoietic reconstitution by Trp53-/-p16Ink4a-/-p19Arf-/- multipotent progenitors.

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onc.2016.478

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3300-3311

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leukemia

Loss of p53 induces leukemic transformation in a murine model of Jak2 V617F-driven polycythemia vera.

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P2860

P2860

Loss of p53 induces leukemic transformation in a murine model of Jak2 V617F-driven polycythemia vera.

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