about
Cellular distribution, regulated expression, and functional role of the anorexigenic peptide, NUCB2/nesfatin-1, in the testisLeptin receptor null mice with reexpression of LepR in GnRHR expressing cells display elevated FSH levels but remain in a prepubertal stateHypothalamic growth hormone receptor (GHR) controls hepatic glucose production in nutrient-sensing leptin receptor (LepRb) expressing neuronsLoss of Ntrk2/Kiss1r signaling in oocytes causes premature ovarian failure.Role of the adipocyte-derived hormone leptin in reproductive controlEffects and interactions of tachykinins and dynorphin on FSH and LH secretion in developing and adult ratsCrowding and Follicular Fate: Spatial Determinants of Follicular Reserve and Activation of Follicular Growth in the Mammalian Ovary.Kisspeptin receptor haplo-insufficiency causes premature ovarian failure despite preserved gonadotropin secretionNeurokinin B and the control of the gonadotropic axis in the rat: developmental changes, sexual dimorphism, and regulation by gonadal steroids.Direct Actions of Kisspeptins on GnRH Neurons Permit Attainment of Fertility but are Insufficient to Fully Preserve Gonadotropic Axis Activity.Role of neurokinin B in the control of female puberty and its modulation by metabolic statusPI3K p110β subunit in leptin receptor expressing cells is required for the acute hypophagia induced by endotoxemia.Defining a novel leptin-melanocortin-kisspeptin pathway involved in the metabolic control of pubertyMetabolic control of puberty onset: new players, new mechanisms.Emerging roles of NUCB2/nesfatin-1 in the metabolic control of reproduction.The anorexigenic neuropeptide, nesfatin-1, is indispensable for normal puberty onset in the female rat.Hypothalamic action of phoenixin to control reproductive hormone secretion in females: importance of the orphan G protein-coupled receptor Gpr173.Alterations in hypothalamic KiSS-1 system in experimental diabetes: early changes and functional consequences.Persistent impairment of hypothalamic KiSS-1 system after exposures to estrogenic compounds at critical periods of brain sex differentiation.Obesity-induced hypogonadism in the male: premature reproductive neuroendocrine senescence and contribution of Kiss1-mediated mechanisms.Characterization of the inhibitory roles of RFRP3, the mammalian ortholog of GnIH, in the control of gonadotropin secretion in the rat: in vivo and in vitro studies.Differential modulation of gonadotropin responses to kisspeptin by aminoacidergic, peptidergic, and nitric oxide neurotransmission.Acute inflammation reduces kisspeptin immunoreactivity at the arcuate nucleus and decreases responsiveness to kisspeptin independently of its anorectic effects.The mammalian target of rapamycin as novel central regulator of puberty onset via modulation of hypothalamic Kiss1 system.Kisspeptin signaling is indispensable for neurokinin B, but not glutamate, stimulation of gonadotropin secretion in mice.Desensitization of gonadotropin responses to kisspeptin in the female rat: analyses of LH and FSH secretion at different developmental and metabolic states.Early metabolic programming of puberty onset: impact of changes in postnatal feeding and rearing conditions on the timing of puberty and development of the hypothalamic kisspeptin system.PI3Kα inactivation in leptin receptor cells increases leptin sensitivity but disrupts growth and reproduction.Sexually dimorphic distribution of Prokr2 neurons revealed by the Prokr2-Cre mouse model.Obesity-Induced Infertility in Male Mice Is Associated With Disruption of Crisp4 Expression and Sperm Fertilization Capacity.AMPKα2 in Kiss1 Neurons Is Required for Reproductive Adaptations to Acute Metabolic Challenges in Adult Female Mice.Critical roles of kisspeptins in female puberty and preovulatory gonadotropin surges as revealed by a novel antagonist.Obesity and high fat diet induce distinct changes in placental gene expression and pregnancy outcome.Physiological roles of gonadotropin-inhibitory hormone signaling in the control of mammalian reproductive axis: studies in the NPFF1 receptor null mouse.Critical Roles of Kisspeptin in Female Puberty and Preovulatory Gonadotropin Surges as Revealed by a Novel Antagonist.Characterization of the reproductive effects of the anorexigenic VGF-derived peptide TLQP-21: in vivo and in vitro studies in male rats.Metabolic regulation of female puberty via hypothalamic AMPK-kisspeptin signalingInsulin signaling in LepR cells modulates fat and glucose homeostasis independent of leptinIL-6 and IGF-1 are independent prognostic factors of liver steatosis and non-alcoholic steatohepatitis in morbidly obese patientsMetabolic programming of puberty: sexually dimorphic responses to early nutritional challenges
P50
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P50
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David García-Galiano
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David García-Galiano
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David García-Galiano
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2000-01-01T00:00:00Z