about
Functional alignment of regulatory networks: a study of temperate phagesPromoter activation by CII, a potent transcriptional activator from bacteriophage 186.Purification of bacteriophage lambda repressorAspects of protein-DNA interactions: a review of quantitative thermodynamic theory for modelling synthetic circuits utilising LacI and CI repressors, IPTG and the reporter gene lacZ.Efficient chromosomal-scale DNA looping in Escherichia coli using multiple DNA-looping elementsRoad rules for traffic on DNA-systematic analysis of transcriptional roadblocking in vivo.Revisited gene regulation in bacteriophage lambda.Quantitation of interactions between two DNA loops demonstrates loop domain insulation in E. coli cells.Transcriptional interference by RNA polymerase pausing and dislodgement of transcription factors.Cro's role in the CI Cro bistable switch is critical for {lambda}'s transition from lysogeny to lytic developmentQuantitation of the DNA tethering effect in long-range DNA looping in vivo and in vitro using the Lac and λ repressors.The role of repressor kinetics in relief of transcriptional interference between convergent promoters.Modelling transcriptional interference and DNA looping in gene regulation.Cooperativity in long-range gene regulation by the lambda CI repressor.Potent transcriptional interference by pausing of RNA polymerases over a downstream promoter.Directing traffic on DNA-How transcription factors relieve or induce transcriptional interference.Bacteriophage lambda repressor mediates the formation of a complex enhancer-like structure.One-step cloning and chromosomal integration of DNA.Programmable DNA looping using engineered bivalent dCas9 complexes.Mechanisms of biotin-regulated gene expression in microbes.Linkages between the dissociation of alpha beta tubulin into subunits and ligand binding: the ground state of tubulin is the GDP conformation.Clonetegration Using OSIP Plasmids: One-Step DNA Assembly and Site-Specific Genomic Integration in Bacteria.Hidden Secrets of Sigma54 Promoters Revealed.Repurposing site-specific recombinases for synthetic biology.Effects of thermodynamic nonideality on the kinetics of ester hydrolysis by alpha-chymotrypsin: a model system with preexistence of the isomerization equilibrium.Biotin-mediated growth and gene expression in Staphylococcus aureus is highly responsive to environmental biotin.Slow growth leads to a switch.Native mass spectrometry identifies an alternative DNA-binding pathway for BirA from Staphylococcus aureusLinkage between ligand binding and control of tubulin conformationSubstrate as a source of thermodynamic nonideality in enzyme kinetic studies: invertase-catalyzed hydrolysis of sucroseThermodynamic nonideality as a probe of reversible protein unfolding effected by variations in pH and temperature: studies of ribonucleaseAllowance for thermodynamic nonideality and Donnan effects in binding studies. Activity coefficients of charged ligands in the presence of albuminEffect of calcium ion on the dimerization of alpha-chymotrypsinThermodynamic nonideality in macromolecular solutions. Evaluation of parameters for the prediction of covolume effectsEffect of colchicine analogues on the dissociation of alpha beta tubulin into subunits: the locus of colchicine bindingThe Tum protein of coliphage 186 is an antirepressorThe structural basis of cooperative regulation at an alternate genetic switchCharacterizing Transcriptional Interference between Converging Genes in BacteriaCombining random microseed matrix screening and the magic triangle for the efficient structure solution of a potential lysin from bacteriophage P68Advanced Resistance Studies Identify Two Discrete Mechanisms in Staphylococcus aureus to Overcome Antibacterial Compounds that Target Biotin Protein Ligase
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Keith Shearwin
@ast
Keith Shearwin
@en
Keith Shearwin
@es
Keith Shearwin
@nl
Keith Shearwin
@sl
type
label
Keith Shearwin
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Keith Shearwin
@en
Keith Shearwin
@es
Keith Shearwin
@nl
Keith Shearwin
@sl
prefLabel
Keith Shearwin
@ast
Keith Shearwin
@en
Keith Shearwin
@es
Keith Shearwin
@nl
Keith Shearwin
@sl
P106
P1153
6603831004
P31
P496
0000-0002-7736-2742