Molecular and neuronal substrate for the selective attenuation of anxiety.
about
Clobazam and its active metabolite N-desmethylclobazam display significantly greater affinities for α₂- versus α₁-GABA(A)-receptor complexesThe benzodiazepine binding site of GABA A receptors as a target for the development of novel anxiolyticsA polymorphism in GABRA2 is associated with the medial frontal response to alcohol cues in an fMRI studyBinge alcohol drinking is associated with GABAA alpha2-regulated Toll-like receptor 4 (TLR4) expression in the central amygdalaVariations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations.GABA A receptors: subtypes provide diversity of function and pharmacologyInternational Union of Pharmacology. LXX. Subtypes of gamma-aminobutyric acid(A) receptors: classification on the basis of subunit composition, pharmacology, and function. UpdatePWZ-029, a compound with moderate inverse agonist functional selectivity at GABA(A) receptors containing alpha5 subunits, improves passive, but not active, avoidance learning in ratsAbuse and dependence liability of benzodiazepine-type drugs: GABA(A) receptor modulation and beyondBehavioral disinhibition and reduced anxiety-like behaviors in monoamine oxidase B-deficient miceGABRG1 and GABRA2 as independent predictors for alcoholism in two populationsSelective labelling of diazepam-insensitive GABAA receptors in vivo using [3H]Ro 15-4513GABAA receptor gamma 2 subunit knockdown mice have enhanced anxiety-like behavior but unaltered hypnotic response to benzodiazepines.Pharmacological treatment of anxiety disorders: current treatments and future directionsStructure, function, and modulation of GABA(A) receptorsAnxiety disorders and GABA neurotransmission: a disturbance of modulationPrinciples of agonist recognition in Cys-loop receptorsGABAA receptor-acting neurosteroids: a role in the development and regulation of the stress responseAnxioselective anxiolytics: on a quest for the Holy GrailIncreased anxiety-like behavior and enhanced synaptic efficacy in the amygdala of GluR5 knockout miceTrace fear conditioning involves hippocampal alpha5 GABA(A) receptorsMolecular mechanisms of antiseizure drug activity at GABAA receptorsSelective anxiolysis produced by ocinaplon, a GABA(A) receptor modulator.α2-containing GABA(A) receptors: a requirement for midazolam-escalated aggression and social approach in miceA Tribute to Peter H Seeburg (1944-2016): A Founding Father of Molecular Neurobiology.GABAA receptor subtypes: Therapeutic potential in Down syndrome, affective disorders, schizophrenia, and autism.Effects of a low dose of ethanol in an animal model of premenstrual anxiety.Benzodiazepine-induced anxiolysis and reduction of conditioned fear are mediated by distinct GABAA receptor subtypes in miceThe autism diagnosis in translation: shared affect in children and mouse models of ASD.Effects of alcohol on the acquisition and expression of fear-potentiated startle in mouse lines selectively bred for high and low alcohol preference.The GABAergic deficit hypothesis of major depressive disorder.Beyond classical benzodiazepines: novel therapeutic potential of GABAA receptor subtypes.Reduction of fear-potentiated startle by benzodiazepines in C57BL/6J mice.The biology of fear- and anxiety-related behaviorsEndocannabinoid system and psychiatry: in search of a neurobiological basis for detrimental and potential therapeutic effects.Behavioral and neural analysis of GABA in the acquisition, consolidation, reconsolidation, and extinction of fear memory.Criteria for validating mouse models of psychiatric diseasesGlutamatergic and GABAergic modulations of ultrasonic vocalizations during maternal separation distress in mouse pups.Validating a human model for anxiety using startle potentiated by cue and context: the effects of alprazolam, pregabalin, and diphenhydramineAmygdala-specific reduction of alpha1-GABAA receptors disrupts the anticonvulsant, locomotor, and sedative, but not anxiolytic, effects of benzodiazepines in mice.
P2860
Q21090654-DDB51C31-C126-4D82-BF9E-783262AA2271Q22306024-A6CEDC74-AEFE-41B5-A12D-0F1B43BAB6A8Q24289139-A1724EC9-A4E6-486A-867B-57A5613E28B9Q24289260-3F2A91AA-4BA8-417D-95CF-C7AC28C74D9DQ24533346-22F5CBD3-82CE-48A4-8D57-8BAE8935283AQ24599057-FD80FAC0-2253-426C-8CF9-A2AE6DEA9187Q24608968-1FF3F510-31AE-467A-8D93-B14AD2268B5DQ24644631-8C7384D9-9F9B-4A92-83D3-CD2D380B0BA5Q24644809-26344404-6355-436D-9BBF-6D4E35792776Q24650165-8790B74A-6B31-4F6B-82FD-A006468AA852Q24657154-A97B8018-892E-4069-A1DC-CEC2D4E031ABQ24676214-ED3E9655-6A7F-416B-9F6F-A325CBDC8716Q24801914-39030120-90C6-481E-96C6-5FE1FFD1B93BQ26851461-0A67B59C-5FE5-4B65-9A82-D60D712A4B59Q26859328-E9E2BC6A-B883-41EF-A252-67A2C29A0458Q27003916-707F6C3D-CECC-405B-B3A3-047891E01AB1Q28239408-84CF5F7E-4B9B-41EF-9695-453B2A34B96DQ28241963-34C26F33-8E26-4E80-A7E7-8E6E35772D79Q28275122-A9ED75B5-19E8-4B1E-801C-6B9226626AF1Q28586201-326BAEC3-35CA-4E19-B3E6-6F6AED7B6474Q28594296-227A541C-F00C-4221-B5D1-931AE158FC0FQ28681145-4144655C-5182-428B-92CE-356070F3F40FQ28972575-AC84A1C8-60D0-4610-B517-D3FAB87ECA92Q30368912-9461F99C-3573-475F-A274-ED483AA774B7Q30396383-CDB6EEBE-CC7A-4273-AFF0-9423E0CE8A1BQ30421260-62A9E687-E53D-43AA-B15F-50109087FD56Q30430592-83B760CC-092A-4F7F-8022-AEEC9E6B9A3FQ30451624-161DD4E4-63DC-4CBC-BB49-9BC790312FF4Q30453436-DAE5B6D6-EF42-4D49-80FC-113EF9E49637Q30461985-907ED5A9-9CE7-4C3B-89EF-ABB4E6556B08Q30464954-7F6056E1-E40E-4FF8-861D-549DD9C81981Q30466591-48AD3A8B-6285-4978-A198-4A6112456A74Q30471085-C8C00383-2A07-4CF5-B7ED-B9018D182C4BQ30473428-62BB760E-7E4A-4C7E-80F6-3AB56ECAF21BQ30473707-560A523E-3985-4B34-A020-0DBC60C82432Q30474984-FF04CD29-E5BE-4A7B-9498-F1463DAC6BBFQ30480118-FB850470-84A3-4288-BC45-2D74BD06393DQ30486159-407A6FBE-24A7-4BFD-8E5B-19BD8E7E7BDEQ30488931-4235282D-0C75-4262-BDD0-81AEB9A91827Q30495530-5A6003D3-C6E6-48F4-88B8-56DA9E325C5F
P2860
Molecular and neuronal substrate for the selective attenuation of anxiety.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh-hant
name
Molecular and neuronal substrate for the selective attenuation of anxiety.
@en
Molecular and neuronal substrate for the selective attenuation of anxiety.
@nl
type
label
Molecular and neuronal substrate for the selective attenuation of anxiety.
@en
Molecular and neuronal substrate for the selective attenuation of anxiety.
@nl
prefLabel
Molecular and neuronal substrate for the selective attenuation of anxiety.
@en
Molecular and neuronal substrate for the selective attenuation of anxiety.
@nl
P2093
P1433
P1476
Molecular and neuronal substrate for the selective attenuation of anxiety
@en
P2093
F Crestani
H Bluethmann
J A Benson
P304
P356
10.1126/SCIENCE.290.5489.131
P407
P577
2000-10-01T00:00:00Z