about
Identification and characterization of two novel mutations in the LPL gene causing type I hyperlipoproteinemiaPNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cellsDEPDC5 variants increase fibrosis progression in Europeans with chronic hepatitis C virus infection.The MBOAT7-TMC4 Variant rs641738 Increases Risk of Nonalcoholic Fatty Liver Disease in Individuals of European Descent.PNPLA3 148M Carriers with Inflammatory Bowel Diseases Have Higher Susceptibility to Hepatic Steatosis and Higher Liver Enzymes.Analysis of aquaporins from the euryhaline barnacle Balanus improvisus reveals differential expression in response to changes in salinity.Telomerase reverse transcriptase germline mutations and hepatocellular carcinoma in patients with nonalcoholic fatty liver disease.Recombinant PNPLA3 protein shows triglyceride hydrolase activity and its I148M mutation results in loss of function.Proinsulin C-peptide modulates the expression of ERK1/2, type I collagen and RANKL in human osteoblast-like cells (Saos-2).PNPLA3 overexpression results in reduction of proteins predisposing to fibrosis.The rs2294918 E434K variant modulates patatin-like phospholipase domain-containing 3 expression and liver damage.Human Multilineage 3D Spheroids as a Model of Liver Steatosis and FibrosisCysteine is not a substrate but a specific modulator of human ASCT2 (SLC1A5) transporterTransport mechanism and regulatory properties of the human amino acid transporter ASCT2 (SLC1A5)
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hulumtues
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0000-0002-2478-225X