Generation of tumor-specific, HLA class I-restricted human Th1 and Tc1 cells by cell engineering with tumor peptide-specific T-cell receptor genes.
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T cell receptor gene therapy for cancerRecent advance in antigen-specific immunotherapy for acute myeloid leukemiaHow (specific) would like your T-cells today? Generating T-cell therapeutic function through TCR-gene transferAdoptive transfer of genetically modified Wilms' tumor 1-specific T cells in a novel malignant skull base meningioma modelDirect tumor recognition by a human CD4(+) T-cell subset potently mediates tumor growth inhibition and orchestrates anti-tumor immune responses.Transduction of human T cells with a novel T-cell receptor confers anti-HCV reactivity.Strategies to overcome obstacles to successful immunotherapy of melanomaMHC-I-restricted melanoma antigen specific TCR-engineered human CD4+ T cells exhibit multifunctional effector and helper responses, in vitroGeneration of diffuse large B cell lymphoma-associated antigen-specific Vα6/Vβ13+T cells by TCR gene transfer.Genetically engineered T cells for the treatment of cancer.Generating HPV specific T helper cells for the treatment of HPV induced malignancies using TCR gene transfer.NCI First International Workshop on The Biology, Prevention and Treatment of Relapse after Allogeneic Hematopoietic Cell Transplantation: report from the committee on prevention of relapse following allogeneic cell transplantation for hematologic maFacilitating matched pairing and expression of TCR chains introduced into human T cells.Antigen-specific cellular immunotherapy of leukemia.Improving T cell therapy for cancer.Adoptive transfer of Tc1 or Tc17 cells elicits antitumor immunity against established melanoma through distinct mechanismsAdult human sarcomas. I. Basic science.T-cell receptor gene transfer by lentiviral vectors in adoptive cell therapy.T-cell receptor gene therapy for cancer: the progress to date and future objectives.Role of T cell receptor affinity in the efficacy and specificity of adoptive T cell therapies.CD4+CD25- T cells transduced to express MHC class I-restricted epitope-specific TCR synthesize Th1 cytokines and exhibit MHC class I-restricted cytolytic effector function in a human melanoma model.Enhanced T cell receptor gene therapy for cancer.Application of adoptive T-cell therapy using tumor antigen-specific T-cell receptor gene transfer for the treatment of human leukemia.Requisite considerations for successful adoptive immunotherapy with engineered T-lymphocytes using tumor antigen-specific T-cell receptor gene transfer.Clinical evaluation of cellular immunotherapy in acute myeloid leukaemia.Adoptive immunotherapy for cancer.Immunotherapy in acute myeloid leukemia.Human leucocyte antigen class I-redirected anti-tumour CD4+ T cells require a higher T cell receptor binding affinity for optimal activity than CD8+ T cells.Establishing guidelines for CAR-T cells: challenges and considerations.Optimizing T-cell receptor gene therapy for hematologic malignancies.Knockdown of T-bet expression in Mart-127-35 -specific T-cell-receptor-engineered human CD4(+) CD25(-) and CD8(+) T cells attenuates effector function.Death receptor-independent activation-induced cell death in human melanoma antigen-specific MHC class I-restricted TCR-engineered CD4 T cellsMismatched human leukocyte antigen class II-restricted CD8⁺ cytotoxic T cells may mediate selective graft-versus-leukemia effects following allogeneic hematopoietic cell transplantation.Long-term phenotypic, functional and genetic stability of cancer-specific T-cell receptor (TCR) alphabeta genes transduced to CD8+ T cells.Antileukemia multifunctionality of CD4(+) T cells genetically engineered by HLA class I-restricted and WT1-specific T-cell receptor gene transfer.A Promising Vector for TCR Gene Therapy: Differential Effect of siRNA, 2A Peptide, and Disulfide Bond on the Introduced TCR Expression.Generation of multi-functional antigen-specific human T-cells by lentiviral TCR gene transfer.Rapid Construction of Antitumor T-cell Receptor Vectors from Frozen Tumors for Engineered T-cell Therapy.Combination immunotherapy with radiation and CpG-based tumor vaccination for the eradication of radio- and immuno-resistant lung carcinoma cells.NY-ESO-1 Based Immunotherapy of Cancer: Current Perspectives.
P2860
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P2860
Generation of tumor-specific, HLA class I-restricted human Th1 and Tc1 cells by cell engineering with tumor peptide-specific T-cell receptor genes.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Generation of tumor-specific, ...... pecific T-cell receptor genes.
@en
Generation of tumor-specific, ...... pecific T-cell receptor genes.
@nl
type
label
Generation of tumor-specific, ...... pecific T-cell receptor genes.
@en
Generation of tumor-specific, ...... pecific T-cell receptor genes.
@nl
prefLabel
Generation of tumor-specific, ...... pecific T-cell receptor genes.
@en
Generation of tumor-specific, ...... pecific T-cell receptor genes.
@nl
P2093
P1433
P1476
Generation of tumor-specific, ...... pecific T-cell receptor genes.
@en
P2093
Daiko Wakita
Haruo Sugiyama
Hiroaki Ikeda
Hironari Niiya
Hiroyuki Miyoshi
Junko Matsuzaki
Kenji Chamoto
Kiyotaka Kuzushima
Masaki Yasukawa
Taichi Azuma
P304
P356
10.1182/BLOOD-2004-09-3663
P407
P577
2005-03-24T00:00:00Z