Molecular chaperone complexes with antagonizing activities regulate stability and activity of the tumor suppressor LKB1.
about
STRAD pseudokinases regulate axogenesis and LKB1 stabilityA Decade of Boon or Burden: What Has the CHIP Ever Done for Cellular Protein Quality Control Mechanism Implicated in Neurodegeneration and Aging?Minireview: hey U(PS): metabolic and proteolytic homeostasis linked via AMPK and the ubiquitin proteasome system.Recent progress on liver kinase B1 (LKB1): expression, regulation, downstream signaling and cancer suppressive function.Carboxyl terminus of HSC70-interacting protein (CHIP) down-regulates NF-κB-inducing kinase (NIK) and suppresses NIK-induced liver injuryLKB1 loss promotes endometrial cancer progression via CCL2-dependent macrophage recruitmentThe double edge of the HSP90-CDC37 chaperone machinery: opposing determinants of kinase stability and activityA genome-wide RNAi screen for enhancers of par mutants reveals new contributors to early embryonic polarity in Caenorhabditis elegans.CHIP protects against cardiac pressure overload through regulation of AMPK.CHIP(-/-)-Mouse Liver: Adiponectin-AMPK-FOXO-Activation Overrides CYP2E1-Elicited JNK1-Activation, Delaying Onset of NASH: Therapeutic Implications.Cardioprotective actions of Notch1 against myocardial infarction via LKB1-dependent AMPK signaling pathway.Targeting the LKB1 tumor suppressor.Skp2-dependent ubiquitination and activation of LKB1 is essential for cancer cell survival under energy stress.Cancer stem-like cell related protein CD166 degrades through E3 ubiquitin ligase CHIP in head and neck cancer.LKB1 Tumor Suppressor: Therapeutic Opportunities Knock when LKB1 Is Inactivated.Metformin pharmacogenomics: a genome-wide association study to identify genetic and epigenetic biomarkers involved in metformin anticancer response using human lymphoblastoid cell lines.LKB1 as a Tumor Suppressor in Uterine Cancer: Mouse Models and Translational Studies.Multiple functions of the E3 ubiquitin ligase CHIP in immunity.Post-translational regulation contributes to the loss of LKB1 expression through SIRT1 deacetylase in osteosarcomas.
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P2860
Molecular chaperone complexes with antagonizing activities regulate stability and activity of the tumor suppressor LKB1.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
2011年學術文章
@zh-hant
name
Molecular chaperone complexes ...... of the tumor suppressor LKB1.
@en
Molecular chaperone complexes ...... of the tumor suppressor LKB1.
@nl
type
label
Molecular chaperone complexes ...... of the tumor suppressor LKB1.
@en
Molecular chaperone complexes ...... of the tumor suppressor LKB1.
@nl
prefLabel
Molecular chaperone complexes ...... of the tumor suppressor LKB1.
@en
Molecular chaperone complexes ...... of the tumor suppressor LKB1.
@nl
P2093
P2860
P356
P1433
P1476
Molecular chaperone complexes ...... y of the tumor suppressor LKB1
@en
P2093
A Vigouroux
P2860
P2888
P304
P356
10.1038/ONC.2011.342
P407
P577
2011-08-22T00:00:00Z