The PI3K/Akt/mTOR pathway is activated in murine lupus nephritis and downregulated by rapamycin.
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Autophagy in Chronic Kidney DiseasesThe Role of Autophagy in Lupus NephritisTuberous sclerosis and fulminant lupus in a young woman.Gene network analysis of bone marrow mononuclear cells reveals activation of multiple kinase pathways in human systemic lupus erythematosus.Current status of lupus nephritis.Metabolic alterations and increased liver mTOR expression precede the development of autoimmune disease in a murine model of lupus erythematosus.The PI3K/Akt/PTEN/mTOR pathway: a fruitful target for inducing cell death in rheumatoid arthritis?RNA-seq Analysis Reveals Unique Transcriptome Signatures in Systemic Lupus Erythematosus Patients with Distinct Autoantibody SpecificitiesActivation of mTOR (mechanistic target of rapamycin) in rheumatic diseases.Lymphocyte signaling: regulation of FoxO transcription factors by microRNAs.NLRP3 inflammasome activation contributes to aldosterone-induced podocyte injury.Roles of mTOR complexes in the kidney: implications for renal disease and transplantation.Immunometabolism in systemic lupus erythematosus.Rapamycin ameliorates proteinuria and restores nephrin and podocin expression in experimental membranous nephropathy.Endoplasmic reticulum stress induces autophagy and apoptosis while inhibiting proliferation and drug resistance in multiple myeloma through the PI3K/Akt/mTOR signaling pathway.Human TTRV30M localization within podocytes in a transgenic mouse model of transthyretin related amyloidosis: does the environment play a role?Hsf-1 affects podocyte markers NPHS1, NPHS2 and WT1 in a transgenic mouse model of TTRVal30Met-related amyloidosis.Contribution and underlying mechanisms of CXCR4 overexpression in patients with systemic lupus erythematosus.Trifluoperazine induces apoptosis through the upregulation of Bax/Bcl‑2 and downregulated phosphorylation of AKT in mesangial cells and improves renal function in lupus nephritis mice.Genetic contributions to lupus nephritis in a multi-ethnic cohort of systemic lupus erythematous patients.Kaposi sarcoma-associated herpesvirus latency locus renders B cells hyperresponsive to secondary infections
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P2860
The PI3K/Akt/mTOR pathway is activated in murine lupus nephritis and downregulated by rapamycin.
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2010 nî lūn-bûn
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name
The PI3K/Akt/mTOR pathway is a ...... nd downregulated by rapamycin.
@en
The PI3K/Akt/mTOR pathway is a ...... nd downregulated by rapamycin.
@nl
type
label
The PI3K/Akt/mTOR pathway is a ...... nd downregulated by rapamycin.
@en
The PI3K/Akt/mTOR pathway is a ...... nd downregulated by rapamycin.
@nl
prefLabel
The PI3K/Akt/mTOR pathway is a ...... nd downregulated by rapamycin.
@en
The PI3K/Akt/mTOR pathway is a ...... nd downregulated by rapamycin.
@nl
P2093
P2860
P356
P1476
The PI3K/Akt/mTOR pathway is a ...... nd downregulated by rapamycin.
@en
P2093
Andreas Passam
Eleftheria Vardaki
Eugene Daphnis
Eva Papadogiorgaki
Ioannis Petrakis
Kostas Giannakakis
Kostas Perakis
Lydia Nakopoulou
Spyros Stratigis
Stavros Stratakis
P2860
P304
P356
10.1093/NDT/GFQ496
P407
P577
2010-08-13T00:00:00Z