about
Chimeric EWSR1-FLI1 regulates the Ewing sarcoma susceptibility gene EGR2 via a GGAA microsatelliteThe second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex diseaseReconstitution of the transcription factor TFIIH: assignment of functions for the three enzymatic subunits, XPB, XPD, and cdk7Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcomaThe oncogenic EWS-FLI1 protein binds in vivo GGAA microsatellite sequences with potential transcriptional activation functionDe novo motif identification improves the accuracy of predicting transcription factor binding sites in ChIP-Seq data analysis.Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse modelMesenchymal stem cell features of Ewing tumors.Antagonism pattern detection between microRNA and target expression in Ewing's sarcoma.Genomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 mutations.The first European interdisciplinary ewing sarcoma research summitCancer-associated SF3B1 mutations affect alternative splicing by promoting alternative branchpoint usage.The ENCCA-WP7/EuroSarc/EEC/PROVABES/EURAMOS 3rd European Bone Sarcoma Networking Meeting/Joint Workshop of EU Bone Sarcoma Translational Research Networks; Vienna, Austria, September 24-25, 2015. Workshop Report.EWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3.Systems biology of Ewing sarcoma: a network model of EWS-FLI1 effect on proliferation and apoptosis.Targeting the epigenetic readers in Ewing sarcoma inhibits the oncogenic transcription factor EWS/Fli1.The orphan nuclear receptor DAX1 is up-regulated by the EWS/FLI1 oncoprotein and is highly expressed in Ewing tumors.Update on Families of Round Cell Sarcomas Other than Classical Ewing Sarcomas.Development of curative therapies for Ewing sarcomas by interdisciplinary cooperative groups in Europe.Oncostatin M is a growth factor for Ewing sarcoma.Targeting the EWSR1-FLI1 oncogene-induced protein kinase PKC-β abolishes ewing sarcoma growth.A new subtype of bone sarcoma defined by BCOR-CCNB3 gene fusion.Zoledronic acid as a new adjuvant therapeutic strategy for Ewing's sarcoma patients.EWS-FLI1 inhibits TNFalpha-induced NFkappaB-dependent transcription in Ewing sarcoma cells.Validated prediction of clinical outcome in sarcomas and multiple types of cancer on the basis of a gene expression signature related to genome complexity.Strong smooth muscle differentiation is dependent on myocardin gene amplification in most human retroperitoneal leiomyosarcomas.Translational Activation of HIF1α by YB-1 Promotes Sarcoma Metastasis.Bone sarcomas: from biology to targeted therapies.Preclinical evidence that use of TRAIL in Ewing's sarcoma and osteosarcoma therapy inhibits tumor growth, prevents osteolysis, and increases animal survival.Loss of connexin43 expression in Ewing's sarcoma cells favors the development of the primary tumor and the associated bone osteolysis.SMARCA4 inactivation defines a group of undifferentiated thoracic malignancies transcriptionally related to BAF-deficient sarcomas.BAFfling pathologies: Alterations of BAF complexes in cancer.Transcriptomic definition of molecular subgroups of small round cell sarcomas.ETV4 is a useful marker for the diagnosis of CIC-rearranged undifferentiated round-cell sarcomas: a study of 127 cases including mimicking lesions.Genetic analyses of undifferentiated small round cell sarcoma identifies a novel sarcoma subtype with a recurrent CRTC1-SS18 gene fusion.[Stem cells and connective-tissue tumors: Ewing's sarcoma].[Cellular origin of Ewing's tumor. A corner of the veil is lifted].PAX3-FOXO1 transgenic zebrafish models identify HES3 as a mediator of rhabdomyosarcoma tumorigenesis.Genomic and transcriptomic characterisation of undifferentiated pleomorphic sarcoma of boneComplete response to CSF1R inhibitor in a translocation variant of teno-synovial giant cell tumor without genomic alteration of the CSF1 gene
P50
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P50
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researcher
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wetenschapper
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հետազոտող
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name
Franck Tirode
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Franck Tirode
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Franck Tirode
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Franck Tirode
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Franck Tirode
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Franck Tirode
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Franck Tirode
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Franck Tirode
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Franck Tirode
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Franck Tirode
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Franck Tirode
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P1053
B-4586-2009
P106
P2798
P31
P3829
P496
0000-0003-4731-7817