Midazolam is metabolized by at least three different cytochrome P450 enzymes.
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Long-term culture of genome-stable bipotent stem cells from adult human liverSummary of information on human CYP enzymes: human P450 metabolism data.Effect of itraconazole and terbinafine on the pharmacokinetics and pharmacodynamics of midazolam in healthy volunteersInhibition of cardiac Kv1.5 potassium current by the anesthetic midazolam: mode of action.Differences in drug pharmacokinetics between East Asians and Caucasians and the role of genetic polymorphisms.Oral Midazolam-Ketamine versus Midazolam alone for Procedural Sedation of Children Undergoing Computed Tomography; a Randomized Clinical TrialClinical implications of CYP3A polymorphisms.Effects of genetic polymorphism of cytochrome P450 enzymes on the pharmacokinetics of benzodiazepines.Differential inhibition of cytochromes P450 3A4 and 3A5 by the newly synthesized coumarin derivatives 7-coumarin propargyl ether and 7-(4-trifluoromethyl)coumarin propargyl ether.Hemodialysis does not alter in vitro hepatic CYP3A4 and CYP2D6 metabolic activity in uremic serum.Analytic reviews: managing the agitated patient in the ICU: sedation, analgesia, and neuromuscular blockade.Pharmacokinetics cannot explain the increased effective dose requirement for morphine and midazolam in rats during their extended administration alone or in combination.Evidence of CYP3A allosterism in vivo: analysis of interaction between fluconazole and midazolam.Flexible bronchoscopy may decrease respiratory muscle strength: premedicational midazolam in focus.Activation of CYP3A-mediated testosterone 6β-hydroxylation by tanshinone IIA and midazolam 1-hydroxylation by cryptotanshinone in human liver microsomes.Effect of mibefradil on CYP3A4 in vivo.CYP3A5 genotype did not impact on nifedipine disposition in healthy volunteers.Effect of ursodeoxycholic acid on the pharmacokinetics of midazolam and CYP3A in the liver and intestine of rats.Effect of borneol on cytochrome P450 3A enzyme and midazolam pharmacokinetics in rats.Case series of buprenorphine injectors in Kuala Lumpur, Malaysia.Effect of atorvastatin and fluvastatin on the metabolism of midazolam by cytochrome P450 in vitro.CYP3A4 intron 6 C>T SNP (CYP3A4*22) encodes lower CYP3A4 activity in cancer patients, as measured with probes midazolam and erythromycin.In vivo CYP3A activity is significantly lower in cyclosporine-treated as compared with tacrolimus-treated renal allograft recipients.Lack of effect of brivanib on the pharmacokinetics of midazolam, a CYP3A4 substrate, administered intravenously and orally in healthy participants.Pharmacokinetics of midazolam tablet in different Chinese ethnic groups.Effect of route of administration of fluconazole on the interaction between fluconazole and midazolam.Midazolam hydroxylation by human liver microsomes in vitro: inhibition by fluoxetine, norfluoxetine, and by azole antifungal agents.
P2860
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P2860
Midazolam is metabolized by at least three different cytochrome P450 enzymes.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
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1994年學術文章
@yue
1994年學術文章
@zh-hant
name
Midazolam is metabolized by at least three different cytochrome P450 enzymes.
@en
Midazolam is metabolized by at least three different cytochrome P450 enzymes.
@nl
type
label
Midazolam is metabolized by at least three different cytochrome P450 enzymes.
@en
Midazolam is metabolized by at least three different cytochrome P450 enzymes.
@nl
prefLabel
Midazolam is metabolized by at least three different cytochrome P450 enzymes.
@en
Midazolam is metabolized by at least three different cytochrome P450 enzymes.
@nl
P2093
P356
P1476
Midazolam is metabolized by at least three different cytochrome P450 enzymes.
@en
P2093
P304
P356
10.1093/BJA/73.5.658
P407
P577
1994-11-01T00:00:00Z