Inferring signaling pathway topologies from multiple perturbation measurements of specific biochemical species.
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Reverse engineering and identification in systems biology: strategies, perspectives and challengesRaf-interactome in tuning the complexity and diversity of Raf function.Automatic generation of predictive dynamic models reveals nuclear phosphorylation as the key Msn2 control mechanism.P38 and JNK have opposing effects on persistence of in vivo leukocyte migration in zebrafish.Combining test statistics and models in bootstrapped model rejection: it is a balancing actA framework for parameter estimation and model selection from experimental data in systems biology using approximate Bayesian computation.Analyzing Th17 cell differentiation dynamics using a novel integrative modeling framework for time-course RNA sequencing data.Data-driven mechanistic analysis method to reveal dynamically evolving regulatory networks.Elucidating the in vivo phosphorylation dynamics of the ERK MAP kinase using quantitative proteomics data and Bayesian model selection.Programming biological models in Python using PySBBayesian model selection validates a biokinetic model for zirconium processing in humans.Finding novel pharmaceuticals in the systems biology era using multiple effective drug targets, phenotypic screening and knowledge of transporters: where drug discovery went wrong and how to fix it.In silico modeling of Itk activation kinetics in thymocytes suggests competing positive and negative IP4 mediated feedbacks increase robustness.Dynamic cross talk model of the epithelial innate immune response to double-stranded RNA stimulation: coordinated dynamics emerging from cell-level noise.Elucidation of Genetic Interactions in the Yeast GATA-Factor Network Using Bayesian Model SelectionIn silico model-based inference: an emerging approach for inverse problems in engineering better medicinesNetwork inference through synergistic subnetwork evolution.Bayesian inference of signaling network topology in a cancer cell line.Near-optimal experimental design for model selection in systems biologyDynamic modeling and analysis of cancer cellular network motifs.Computational approaches for analyzing information flow in biological networks.A Bayesian approach to estimating hidden variables as well as missing and wrong molecular interactions in ordinary differential equation-based mathematical models.The response of cancers to BRAF inhibition underscores the importance of cancer systems biology.Competing G protein-coupled receptor kinases balance G protein and β-arrestin signaling.A dynamic network model of mTOR signaling reveals TSC-independent mTORC2 regulation.Statistical analysis of nonlinear dynamical systems using differential geometric sampling methodsProperties of cell death models calibrated and compared using Bayesian approaches.Deregulated expression of TANK in glioblastomas triggers pro-tumorigenic ERK1/2 and AKT signaling pathways.Markov chain Monte Carlo inference for Markov jump processes via the linear noise approximation.A logic-based method to build signaling networks and propose experimental plans.
P2860
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P2860
Inferring signaling pathway topologies from multiple perturbation measurements of specific biochemical species.
description
2010 nî lūn-bûn
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2010年の論文
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2010年学术文章
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2010年学术文章
@zh
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
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2010年學術文章
@zh-hant
name
Inferring signaling pathway to ...... specific biochemical species.
@en
Inferring signaling pathway to ...... specific biochemical species.
@nl
type
label
Inferring signaling pathway to ...... specific biochemical species.
@en
Inferring signaling pathway to ...... specific biochemical species.
@nl
prefLabel
Inferring signaling pathway to ...... specific biochemical species.
@en
Inferring signaling pathway to ...... specific biochemical species.
@nl
P2093
P50
P1433
P1476
Inferring signaling pathway to ...... specific biochemical species.
@en
P2093
Allan J Dunlop
Amélie Gormand
Dominic Ketley
George S Baillie
Graeme Milligan
Tian-Rui Xu
Vladislav Vyshemirsky
P356
10.1126/SCISIGNAL.2000517
P577
2010-01-01T00:00:00Z