Biosensor reveals multiple sources for mitochondrial NAD⁺.
about
Undercover: gene control by metabolites and metabolic enzymesUrinary and Fecal Metabonomics Study of the Protective Effect of Chaihu-Shu-Gan-San on Antibiotic-Induced Gut Microbiota Dysbiosis in Rats.Chemical signaling between gut microbiota and host chromatin: What is your gut really saying?The effector AvrRxo1 phosphorylates NAD in planta.PARPs and ADP-ribosylation: recent advances linking molecular functions to biological outcomes.Chemosensitivity of IDH1-Mutated Gliomas Due to an Impairment in PARP1-Mediated DNA Repair.Nicotinamide Adenine Dinucleotide Metabolism and Neurodegeneration.ATM induces MacroD2 nuclear export upon DNA damageGenetically encoded fluorescent sensors reveal dynamic regulation of NADPH metabolism.PARP inhibitors as antitumor agents: a patent update (2013-2015).Recent developments of genetically encoded optical sensors for cell biology.NAD and the aging process: Role in life, death and everything in between.Traditional and novel tools to probe the mitochondrial metabolism in health and disease.NAD(+) : a key metabolic regulator with great therapeutic potential.Circadian Oscillations of NADH Redox State Using a Heterologous Metabolic Sensor in Mammalian Cells.Using Fractional Intensities of Time-resolved Fluorescence to Sensitively Quantify NADH/NAD+ with Genetically Encoded Fluorescent BiosensorsCircadian and Feeding Rhythms Orchestrate the Diurnal Liver Acetylome.Alterations in fatty acid metabolism and sirtuin signaling characterize early type-2 diabetic hearts of fructose-fed ratsPre-B-cell colony-enhancing factor as a target for protecting against apoptotic neuronal death and mitochondrial damage in ischemia.NMNAT3 is protective against the effects of neonatal cerebral hypoxia-ischemia.The Alkylating Chemotherapeutic Temozolomide Induces Metabolic Stress in IDH1-Mutant Cancers and Potentiates NAD+ Depletion-Mediated Cytotoxicity.MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD+ consumption.Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases.CD38 knockout suppresses tumorigenesis in mice and clonogenic growth of human lung cancer cells.Specificity of reversible ADP-ribosylation and regulation of cellular processes.Metabolic control by sirtuins and other enzymes that sense NAD+, NADH, or their ratio.Nicotinamide phosphoribosyltransferase delays cellular senescence by upregulating SIRT1 activity and antioxidant gene expression in mouse cells.Metabolic intermediates - Cellular messengers talking to chromatin modifiers.Identification of Protein Substrates of Specific PARP Enzymes Using Analog-Sensitive PARP Mutants and a "Clickable" NAD+ Analog.Spatiotemporal Compartmentalization of Hepatic NADH and NADPH metabolism.The Pharmacology of CD38/NADase: An Emerging Target in Cancer and Diseases of Aging.The Emergence of the Nicotinamide Riboside Kinases in the regulation of NAD+ Metabolism.Semisynthetic biosensors for mapping cellular concentrations of nicotinamide adenine dinucleotides.Nicotinamide adenine dinucleotide is transported into mammalian mitochondria.The MacroH2A1.1 - PARP1 Axis at the Intersection Between Stress Response and Metabolism
P2860
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P2860
Biosensor reveals multiple sources for mitochondrial NAD⁺.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh-hant
name
Biosensor reveals multiple sources for mitochondrial NAD⁺.
@en
Biosensor reveals multiple sources for mitochondrial NAD⁺.
@nl
type
label
Biosensor reveals multiple sources for mitochondrial NAD⁺.
@en
Biosensor reveals multiple sources for mitochondrial NAD⁺.
@nl
prefLabel
Biosensor reveals multiple sources for mitochondrial NAD⁺.
@en
Biosensor reveals multiple sources for mitochondrial NAD⁺.
@nl
P2093
P2860
P356
P1433
P1476
Biosensor reveals multiple sources for mitochondrial NAD⁺.
@en
P2093
Amber M Jones-Brunette
David L Farrens
DongHo Kim
Melissa L Stewart
Michael S Cohen
Richard H Goodman
Xiaolu A Cambronne
P2860
P304
P356
10.1126/SCIENCE.AAD5168
P407
P577
2016-06-01T00:00:00Z