Streptococcus pneumoniae evades complement attack and opsonophagocytosis by expressing the pspC locus-encoded Hic protein that binds to short consensus repeats 8-11 of factor H.
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Streptococcus pneumoniae capsular serotype 19F is more resistant to C3 deposition and less sensitive to opsonophagocytosis than serotype 6BHuman pathogenic Borrelia spielmanii sp. nov. resists complement-mediated killing by direct binding of immune regulators factor H and factor H-like protein 1Molecular basis of host specificity in human pathogenic bacteriaComplement Evasion Mediated by Enhancement of Captured Factor H: Implications for Protection of Self-Surfaces from ComplementStaphylococcus aureus surface protein SdrE binds complement regulator factor H as an immune evasion tacticBorrelia burgdorferi complement regulator-acquiring surface protein 2 does not contribute to complement resistance or host infectivity.Factor H binds to washed human platelets.Yersinia enterocolitica serum resistance proteins YadA and ail bind the complement regulator C4b-binding protein.Role of complement in host defense against pneumococcal otitis mediaSelf-nonself discrimination by the complement system.Impact of the SpeB protease on binding of the complement regulatory proteins factor H and factor H-like protein 1 by Streptococcus pyogenes.A novel monoclonal antibody against FbaA can inhibit the binding of the complement regulatory protein factor H to group A streptococcus.Differential PsaA-, PspA-, PspC-, and PdB-specific immune responses in a mouse model of pneumococcal carriage.Interaction of pneumococcal histidine triad proteins with human complement.Mapping of epitopes recognized by antibodies induced by immunization of mice with PspA and PspC.The human complement regulator factor H binds pneumococcal surface protein PspC via short consensus repeats 13 to 15.Identification of acidic pH-dependent ligands of pentameric C-reactive protein.The capsular serotype of Streptococcus pneumoniae is more important than the genetic background for resistance to complement.Serotype-related variation in susceptibility to complement deposition and opsonophagocytosis among clinical isolates of Streptococcus pneumoniaeDisruption of the alternative pathway convertase occurs at the staphylococcal surface via the acquisition of factor H by Staphylococcus aureus.A meningococcal factor H binding protein mutant that eliminates factor H binding enhances protective antibody responses to vaccinationContribution of different pneumococcal virulence factors to experimental meningitis in mice.Expression of innate immune complement regulators on brain epithelial cells during human bacterial meningitisHuman L-ficolin, a recognition molecule of the lectin activation pathway of complement, activates complement by binding to pneumolysin, the major toxin of Streptococcus pneumoniae.The contribution of PspC to pneumococcal virulence varies between strains and is accomplished by both complement evasion and complement-independent mechanismsTwo DHH subfamily 1 proteins contribute to pneumococcal virulence and confer protection against pneumococcal disease.Essential role of factor B of the alternative complement pathway in complement activation and opsonophagocytosis during acute pneumococcal otitis media in mice.C-reactive protein protects mice against pneumococcal infection via both phosphocholine-dependent and phosphocholine-independent mechanisms.A survey of the year 2002 commercial optical biosensor literature.ZmpB, a novel virulence factor of Streptococcus pneumoniae that induces tumor necrosis factor alpha production in the respiratory tractCross-reactivity of antipneumococcal surface protein C (PspC) antibodies with different strains and evaluation of inhibition of human complement factor H and secretory IgA binding via PspC.Factor H binding to PspC of Streptococcus pneumoniae increases adherence to human cell lines in vitro and enhances invasion of mouse lungs in vivoMultivalent Pneumococcal Protein Vaccines Comprising Pneumolysoid with Epitopes/Fragments of CbpA and/or PspA Elicit Strong and Broad Protection.Fhb, a novel factor H-binding surface protein, contributes to the antiphagocytic ability and virulence of Streptococcus suis.Design of meningococcal factor H binding protein mutant vaccines that do not bind human complement factor H.Immunization with Pneumococcal Surface Protein K of Nonencapsulated Streptococcus pneumoniae Provides Protection in a Mouse Model of Colonization.Effects of PspA and antibodies to PspA on activation and deposition of complement on the pneumococcal surface.PspA and PspC minimize immune adherence and transfer of pneumococci from erythrocytes to macrophages through their effects on complement activation.Modulation of nasopharyngeal innate defenses by viral coinfection predisposes individuals to experimental pneumococcal carriagePeritoneal challenge modulates expression of pneumococcal surface protein C during bacteremia in mice.
P2860
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P2860
Streptococcus pneumoniae evades complement attack and opsonophagocytosis by expressing the pspC locus-encoded Hic protein that binds to short consensus repeats 8-11 of factor H.
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年学术文章
@zh-hans
2002年学术文章
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name
Streptococcus pneumoniae evade ...... nsus repeats 8-11 of factor H.
@en
Streptococcus pneumoniae evade ...... nsus repeats 8-11 of factor H.
@nl
type
label
Streptococcus pneumoniae evade ...... nsus repeats 8-11 of factor H.
@en
Streptococcus pneumoniae evade ...... nsus repeats 8-11 of factor H.
@nl
prefLabel
Streptococcus pneumoniae evade ...... nsus repeats 8-11 of factor H.
@en
Streptococcus pneumoniae evade ...... nsus repeats 8-11 of factor H.
@nl
P2093
P1476
Streptococcus pneumoniae evade ...... nsus repeats 8-11 of factor H.
@en
P2093
Hanna Jarva
Jens Hellwage
Lars Björck
Robert Janulczyk
Seppo Meri
P304
P356
10.4049/JIMMUNOL.168.4.1886
P407
P577
2002-02-01T00:00:00Z