A p53-dependent tumor suppressor network is induced by selective miR-125a-5p inhibition in multiple myeloma cells. - Wikidata - wikimedia - TriplyDB

A p53-dependent tumor suppressor network is induced by selective miR-125a-5p inhibition in multiple myeloma cells.

A p53-dependent tumor suppressor network is induced by selective miR-125a-5p inhibition in multiple myeloma cells.

http://www.wikidata.org/entity/Q51735874

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MicroRNAs: Novel Crossroads between Myeloma Cells and the Bone Marrow Microenvironment MicroRNAs in multiple myeloma and related bone disease Molecular Mechanisms of p53 Deregulation in Cancer: An Overview in Multiple Myeloma miR-125a-3p targets MTA1 to suppress NSCLC cell proliferation, migration, and invasion.Association between miR-125a rs12976445 and survival in breast cancer patients Involvement of multiple myeloma cell-derived exosomes in osteoclast differentiation.Selective targeting of IRF4 by synthetic microRNA-125b-5p mimics induces anti-multiple myeloma activity in vitro and in vivo.Rs12976445 Polymorphism is Associated with Risk of Diabetic Nephropathy Through Modulating Expression of MicroRNA-125 and Interleukin-6R.A 13 mer LNA-i-miR-221 Inhibitor Restores Drug Sensitivity in Melphalan-Refractory Multiple Myeloma Cells.Exosomal miR-10a derived from amniotic fluid stem cells preserves ovarian follicles after chemotherapy.MiR-125a-5p decreases after long non-coding RNA HOTAIR knockdown to promote cancer cell apoptosis by releasing caspase 2 Metabolic pathways regulated by TAp73 in response to oxidative stress Mir-34: a new weapon against cancer?miR-23b/SP1/c-myc forms a feed-forward loop supporting multiple myeloma cell growth.Myeloid-derived suppressor cells in multiple myeloma: pre-clinical research and translational opportunities.Differential expression of microRNA in the lungs of rats with pulmonary arterial hypertension.miR-29s: a family of epi-miRNAs with therapeutic implications in hematologic malignancies.Involvement of miR-125a in resistance to daunorubicin by inhibiting apoptosis in leukemia cell lines.Mir-221/222 are promising targets for innovative anticancer therapy.Inhibition of miR-21 restores RANKL/OPG ratio in multiple myeloma-derived bone marrow stromal cells and impairs the resorbing activity of mature osteoclasts.Microenvironment drug resistance in multiple myeloma: emerging new players.Role of micro-RNAs in drug resistance of multiple myeloma.microRNA expression signatures of gastrointestinal stromal tumours: associations with imatinib resistance and patient outcome.Epigenetic modifications in multiple myeloma: recent advances on the role of DNA and histone methylation.MicroRNA Transfer Between Bone Marrow Adipose and Multiple Myeloma Cells.Pharmacokinetics and Pharmacodynamics of a 13-mer LNA-inhibitor-miR-221 in Mice and Non-human Primates.Disentangling the microRNA regulatory milieu in multiple myeloma: integrative genomics analysis outlines mixed miRNA-TF circuits and pathway-derived networks modulated in t(4;14) patients.miR-27 and miR-125 Distinctly Regulate Muscle-Enriched Transcription Factors in Cardiac and Skeletal Myocytes.Integrated analysis of microRNAs, transcription factors and target genes expression discloses a specific molecular architecture of hyperdiploid multiple myeloma Integrative Analysis with Monte Carlo Cross-Validation Reveals miRNAs Regulating Pathways Cross-Talk in Aggressive Breast Cancer.Role of tumor suppressor p53 and micro-RNA interplay in multiple myeloma pathogenesis.MicroRNA-125a-5p alleviates the deleterious effects of ox-LDL on multiple functions of human brain microvessel endothelial cells.The zebrafish miR-125c is induced under hypoxic stress via hypoxia-inducible factor 1α and functions in cellular adaptations and embryogenesis.Evidence of novel miR-34a-based therapeutic approaches for multiple myeloma treatment.Inhibition of EZH2 triggers the tumor suppressive miR-29b network in multiple myeloma.A step-by-step microRNA guide to cancer development and metastasis.Old and Young Actors Playing Novel Roles in the Drama of Multiple Myeloma Bone Marrow Microenvironment Dependent Drug Resistance.Mouse models of multiple myeloma: technologic platforms and perspectives.TIMP-1 downregulation modulates miR-125a-5p expression and triggers the apoptotic pathway.The potential function of microRNAs as biomarkers and therapeutic targets in multiple myeloma.

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P2860

A p53-dependent tumor suppressor network is induced by selective miR-125a-5p inhibition in multiple myeloma cells.

http://www.wikidata.org/entity/Q51735874

description

2014 nî lūn-bûn

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2014年の論文

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年學術文章

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2014年學術文章

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name

A p53-dependent tumor suppress ...... ion in multiple myeloma cells.

@en

A p53-dependent tumor suppress ...... ion in multiple myeloma cells.

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type

label

A p53-dependent tumor suppress ...... ion in multiple myeloma cells.

@en

A p53-dependent tumor suppress ...... ion in multiple myeloma cells.

@nl

prefLabel

A p53-dependent tumor suppress ...... ion in multiple myeloma cells.

@en

A p53-dependent tumor suppress ...... ion in multiple myeloma cells.

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Journal of Cellular Physiology

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A p53-dependent tumor suppress ...... tion in multiple myeloma cells

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P2093

Emanuela Leone

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Lavinia Biamonte

http://www.w3.org/2001/XMLSchema#string

Maria Rita Pitari

http://www.w3.org/2001/XMLSchema#string

Marzia Leotta

http://www.w3.org/2001/XMLSchema#string

Nicola Amodio

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Pierfrancesco Tassone

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Pierosandro Tagliaferri

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P2860

Identification of mammalian microRNA host genes and transcription units

Downregulation of p53-inducible microRNAs 192, 194, and 215 impairs the p53/MDM2 autoregulatory loop in multiple myeloma development

MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis

MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals

MicroRNA profiling: approaches and considerations

Optimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies

Drug resistance in multiple myeloma: latest findings and new concepts on molecular mechanisms.

Clinical significance of TP53 mutation in myeloma.

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

MicroRNAs: genomics, biogenesis, mechanism, and function

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12

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229

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Lavinia Raimondi

Antonio Giordano

Domenica Ronchetti

Maria Teresa Di Martino

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2014-12-01T00:00:00Z

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24819167

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