Targeting the proliferative and chemoresistant compartment in chronic lymphocytic leukemia by inhibiting survivin protein.
about
Synergistic Activity of Deguelin and Fludarabine in Cells from Chronic Lymphocytic Leukemia Patients and in the New Zealand Black Murine ModelCo-culture of primary CLL cells with bone marrow mesenchymal cells, CD40 ligand and CpG ODN promotes proliferation of chemoresistant CLL cells phenotypically comparable to those proliferating in vivoJanus and PI3-kinases mediate glucocorticoid resistance in activated chronic leukemia cells.Essential Role for Survivin in the Proliferative Expansion of Progenitor and Mature B Cells.High-content screening identifies kinase inhibitors that overcome venetoclax resistance in activated CLL cellsFactors involved in CLL pathogenesis and cell survival are disrupted by differentiation of CLL B-cells into antibody-secreting cells.Anti-leukemic effects of the V-ATPase inhibitor Archazolid A.Modeling the chronic lymphocytic leukemia microenvironment in vitro.Inhibition of BCR signaling using the Syk inhibitor TAK-659 prevents stroma-mediated signaling in chronic lymphocytic leukemia cells.Microenvironment regulates the expression of miR-21 and tumor suppressor genes PTEN, PIAS3 and PDCD4 through ZAP-70 in chronic lymphocytic leukemia.
P2860
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P2860
Targeting the proliferative and chemoresistant compartment in chronic lymphocytic leukemia by inhibiting survivin protein.
description
2014 nî lūn-bûn
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name
Targeting the proliferative an ...... y inhibiting survivin protein.
@en
Targeting the proliferative an ...... y inhibiting survivin protein.
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type
label
Targeting the proliferative an ...... y inhibiting survivin protein.
@en
Targeting the proliferative an ...... y inhibiting survivin protein.
@nl
prefLabel
Targeting the proliferative an ...... y inhibiting survivin protein.
@en
Targeting the proliferative an ...... y inhibiting survivin protein.
@nl
P2093
P2860
P50
P356
P1433
P1476
Targeting the proliferative an ...... by inhibiting survivin protein
@en
P2093
P2860
P2888
P304
P356
10.1038/LEU.2014.96
P577
2014-03-12T00:00:00Z