Caveolin-associated accumulation of globotriaosylceramide in the vascular endothelium of alpha-galactosidase A null mice.

Caveolin-associated accumulation of globotriaosylceramide in the vascular endothelium of alpha-galactosidase A null mice.

Item
http://www.wikidata.org/entity/Q51797150
Substrate reduction augments the efficacy of enzyme therapy in a mouse model of Fabry diseaseCase study on the pathophysiology of Fabry disease: abnormalities of cellular membranes can be reversed by substrate reduction in vitro.The development and use of small molecule inhibitors of glycosphingolipid metabolism for lysosomal storage diseases.Establishing 3-nitrotyrosine as a biomarker for the vasculopathy of Fabry disease.Globotriaosylceramide induces oxidative stress and up-regulates cell adhesion molecule expression in Fabry disease endothelial cells.Differential involvement of COX1 and COX2 in the vasculopathy associated with the alpha-galactosidase A-knockout mouse.Decreased nitric oxide bioavailability in a mouse model of Fabry disease.Vascular dysfunction in the alpha-galactosidase A-knockout mouse is an endothelial cell-, plasma membrane-based defect.Endothelial nitric oxide synthase uncoupling and microvascular dysfunction in the mesentery of mice deficient in α-galactosidase A.Molecular biology of atherosclerosis.Enhanced endothelial delivery and biochemical effects of α-galactosidase by ICAM-1-targeted nanocarriers for Fabry disease.Mapping mechanisms and charting the time course of premature cell senescence and apoptosis: lysosomal dysfunction and ganglioside accumulation in endothelial cells.Glycosphingolipid Mediated Caveolin-1 Oligomerization.Co-administration with the pharmacological chaperone AT1001 increases recombinant human α-galactosidase A tissue uptake and improves substrate reduction in Fabry mice.
P2860

Caveolin-associated accumulation of globotriaosylceramide in the vascular endothelium of alpha-galactosidase A null mice.

Item
http://www.wikidata.org/entity/Q51797150
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Caveolin-associated accumulati ...... pha-galactosidase A null mice.
@en
Caveolin-associated accumulati ...... pha-galactosidase A null mice.
@nl
type
label
Caveolin-associated accumulati ...... pha-galactosidase A null mice.
@en
Caveolin-associated accumulati ...... pha-galactosidase A null mice.
@nl
prefLabel
Caveolin-associated accumulati ...... pha-galactosidase A null mice.
@en
Caveolin-associated accumulati ...... pha-galactosidase A null mice.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921
P356
P1433
P1476
Caveolin-associated accumulati ...... pha-galactosidase A null mice.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P921