Crotamine mediates gene delivery into cells through the binding to heparan sulfate proteoglycans.
about
Co-development of diagnostic vectors to support targeted therapies and theranostics: essential tools in personalized cancer therapyThe Rise and Fall of an Evolutionary Innovation: Contrasting Strategies of Venom Evolution in Ancient and Young AnimalsDNA-interactive properties of crotamine, a cell-penetrating polypeptide and a potential drug carrierHuman-protein-derived peptides for intracellular delivery of biomolecules.A Heparan Sulfate-Binding Cell Penetrating Peptide for Tumor Targeting and Migration Inhibition.Cytosolic flagellin-induced lysosomal pathway regulates inflammasome-dependent and -independent macrophage responsesDirect peptide interaction with surface glycosaminoglycans contributes to the cell penetration of maurocalcine.State of the art in the studies on crotamine, a cell penetrating peptide from South American rattlesnake.Heparan sulfate proteoglycans: structure, protein interactions and cell signaling.Advances in targeted therapeutic agents.Cell penetration: scope and limitations by the application of cell-penetrating peptides.Privileged frameworks from snake venom.Insights into the uptake mechanism of NrTP, a cell-penetrating peptide preferentially targeting the nucleolus of tumour cells.Crotamine toxicity and efficacy in mouse models of melanoma.Crotamine, a cell-penetrating peptide, is able to translocate parthenogenetic and in vitro fertilized bovine embryos but does not improve exogenous DNA expression.Design of a disulfide-less, pharmacologically inert, and chemically competent analog of maurocalcine for the efficient transport of impermeant compounds into cells.Revised role of glycosaminoglycans in TAT protein transduction domain-mediated cellular transduction.Oral treatment with a rattlesnake native polypeptide crotamine efficiently inhibits the tumor growth with no potential toxicity for the host animal and with suggestive positive effects on animal metabolic profile.Evaluation in zebrafish model of the toxicity of rhodamine B-conjugated crotamine, a peptide potentially useful for diagnostics and therapeutics.Effect of crotamine, a cell-penetrating peptide, on blastocyst production and gene expression of in vitro fertilized bovine embryos.Crotamine induces browning of adipose tissue and increases energy expenditure in mice.Mechanistic insights into the efficacy of cell penetrating peptide-based cancer vaccines.Pharmacological characterization of crotamine effects on mice hind limb paralysis employing both ex vivo and in vivo assays: Insights into the involvement of voltage-gated ion channels in the crotamine action on skeletal muscles
P2860
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P2860
Crotamine mediates gene delivery into cells through the binding to heparan sulfate proteoglycans.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Crotamine mediates gene delive ...... heparan sulfate proteoglycans.
@en
Crotamine mediates gene delive ...... heparan sulfate proteoglycans.
@nl
type
label
Crotamine mediates gene delive ...... heparan sulfate proteoglycans.
@en
Crotamine mediates gene delive ...... heparan sulfate proteoglycans.
@nl
prefLabel
Crotamine mediates gene delive ...... heparan sulfate proteoglycans.
@en
Crotamine mediates gene delive ...... heparan sulfate proteoglycans.
@nl
P2093
P2860
P50
P356
P1476
Crotamine mediates gene delive ...... heparan sulfate proteoglycans
@en
P2093
Alexandre Kerkis
Eduardo B Oliveira
Fábio Dupart Nascimento
Irina Kerkis
Mirian A F Hayashi
Tetsuo Yamane
Vitor Oliveira
P2860
P304
21349-21360
P356
10.1074/JBC.M604876200
P407
P577
2007-05-09T00:00:00Z