Receptor subtype-specific docking of Asp6.59 with C-terminal arginine residues in Y receptor ligands.
about
Computational prediction of alanine scanning and ligand binding energetics in G-protein coupled receptorsNeuropeptide Y (NPY) in cerebrospinal fluid from patients with Huntington's Disease: increased NPY levels and differential degradation of the NPY1-30 fragment.Position and length of fatty acids strongly affect receptor selectivity pattern of human pancreatic polypeptide analogues.Ligand-induced internalization and recycling of the human neuropeptide Y2 receptor is regulated by its carboxyl-terminal tail.A parallel semisynthetic approach for structure-activity relationship studies of peptide YY.Novel dimeric DOTA-coupled peptidic Y1-receptor antagonists for targeting of neuropeptide Y receptor-expressing cancers.Ligand-mimicking receptor variant discloses binding and activation mode of prolactin-releasing peptide.Central nervous system neuropeptide Y signaling via the Y1 receptor partially dissociates feeding behavior from lipoprotein metabolism in lean rats.Illuminating the life of GPCRsPancreatic polypeptide is recognized by two hydrophobic domains of the human Y4 receptor binding pocket.Neuropeptide Y receptors: ligand binding and trafficking suggest novel approaches in drug development.Neuropeptide Y receptors: how to get subtype selectivityThe Arg-Phe-amide peptide 26RFa/QRFP and its Receptor. IUPHAR Review.Functional reconstitution of human neuropeptide Y (NPY) Y(2) and Y(4) receptors in Sf9 insect cells.Unwinding of the C-Terminal Residues of Neuropeptide Y is critical for Y₂ Receptor Binding and Activation.Selective mode of action of guanidine-containing non-peptides at human NPFF receptors.Molecular basis of agonist docking in a human GPR103 homology model by site-directed mutagenesis and structure-activity relationship studies.Analysis of multiple polymorphisms in the bovine neuropeptide Y5 receptor gene and structural modelling of the encoded protein.Cloning, expression, and ligand-binding characterization of two neuropeptide Y receptor subtypes in orange-spotted grouper, Epinephelus coioides.A Deep Hydrophobic Binding Cavity is the Main Interaction for Different Y2 R Antagonists.C-terminal motif of human neuropeptide Y4 receptor determines internalization and arrestin recruitment.Application of the guanidine-acylguanidine bioisosteric approach to argininamide-type NPY Y₂ receptor antagonists.Molecular characterization of the ligand binding site of the human galanin receptor type 2, identifying subtype selective interactions.Proteolytic degradation of neuropeptide Y (NPY) from head to toe: Identification of novel NPY-cleaving peptidases and potential drug interactions in CNS and Periphery.Structural basis of ligand binding modes at the neuropeptide Y Y1 receptor.
P2860
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P2860
Receptor subtype-specific docking of Asp6.59 with C-terminal arginine residues in Y receptor ligands.
description
2007 nî lūn-bûn
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2007年の論文
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2007年学术文章
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2007年学术文章
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2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
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2007年學術文章
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2007年學術文章
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name
Receptor subtype-specific dock ...... esidues in Y receptor ligands.
@en
Receptor subtype-specific dock ...... esidues in Y receptor ligands.
@nl
type
label
Receptor subtype-specific dock ...... esidues in Y receptor ligands.
@en
Receptor subtype-specific dock ...... esidues in Y receptor ligands.
@nl
prefLabel
Receptor subtype-specific dock ...... esidues in Y receptor ligands.
@en
Receptor subtype-specific dock ...... esidues in Y receptor ligands.
@nl
P2093
P2860
P356
P1476
Receptor subtype-specific dock ...... residues in Y receptor ligands
@en
P2093
Annette G Beck-Sickinger
Holger Römpler
Karin Mörl
Nadine Rabe
Nicole Merten
Torsten Schöneberg
P2860
P304
P356
10.1074/JBC.M608902200
P407
P577
2007-01-04T00:00:00Z