Comprehensive analysis of distinctive polyketide and nonribosomal peptide structural motifs encoded in microbial genomes.
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A computational screen for type I polyketide synthases in metagenomics shotgun dataKEGG for linking genomes to life and the environmentTowards prediction of metabolic products of polyketide synthases: an in silico analysisA hybrid NRPS-PKS gene cluster related to the bleomycin family of antitumor antibiotics in Alteromonas macleodii strainsLegionella shows a diverse secondary metabolism dependent on a broad spectrum Sfp-type phosphopantetheinyl transferaseComputational approaches to natural product discoveryThe origins of specificity in polyketide synthase protein interactions.In silico analysis of methyltransferase domains involved in biosynthesis of secondary metabolites.Structural pattern matching of nonribosomal peptides.Automated genome mining for natural products.Computational identification and analysis of orphan assembly-line polyketide synthases.SBSPKS: structure based sequence analysis of polyketide synthasesNatural product biosynthetic gene diversity in geographically distinct soil microbiomes.Classification of the adenylation and acyl-transferase activity of NRPS and PKS systems using ensembles of substrate specific hidden Markov modelsGenomic and metabolic comparison with Dickeya dadantii 3937 reveals the emerging Dickeya solani potato pathogen to display distinctive metabolic activities and T5SS/T6SS-related toxin repertoire.Genome mining reveals unlocked bioactive potential of marine Gram-negative bacteria.Isolation, abundance and phylogenetic affiliation of endophytic actinomycetes associated with medicinal plants and screening for their in vitro antimicrobial biosynthetic potential.IMG-ABC: A Knowledge Base To Fuel Discovery of Biosynthetic Gene Clusters and Novel Secondary Metabolites.Identification and Heterologous Expression of the Chaxamycin Biosynthesis Gene Cluster from Streptomyces leeuwenhoekiiDiscovery of MRSA active antibiotics using primary sequence from the human microbiome.Genomes to natural products PRediction Informatics for Secondary Metabolomes (PRISM)Detection of antibiotic-resistant bacteria endowed with antimicrobial activity from a freshwater lake and their phylogenetic affiliation.Evolution and taxonomic distribution of nonribosomal peptide and polyketide synthases.Emergent gene order in a model of modular polyketide synthases.Production of Potent Antimicrobial Compounds from Streptomyces cyaneofuscatus Associated with Fresh Water Sediment.Genome-guided discovery of diverse natural products from Burkholderia sp.Polyketide stereocontrol: a study in chemical biology.Engineering the acyltransferase substrate specificity of assembly line polyketide synthases.Engineering antibiotic production and overcoming bacterial resistance.A genomic approach to the cryptic secondary metabolome of the anaerobic world.Bioinformatics tools for genome mining of polyketide and non-ribosomal peptides.A natural prodrug activation mechanism in the biosynthesis of nonribosomal peptides.Progress challenges and opportunities for the re-engineering of trans-AT polyketide synthases.SANDPUMA: Ensemble Predictions of Nonribosomal Peptide Chemistry Reveals Biosynthetic Diversity across Actinobacteria.Non-ribosomal peptide synthetases: Identifying the cryptic gene clusters and decoding the natural product.antiSMASH 4.0-improvements in chemistry prediction and gene cluster boundary identification.Identification of Secondary Metabolite Gene Clusters in the Pseudovibrio Genus Reveals Encouraging Biosynthetic Potential toward the Production of Novel Bioactive Compounds.ClustScan: an integrated program package for the semi-automatic annotation of modular biosynthetic gene clusters and in silico prediction of novel chemical structures.Prediction of monomer isomery in Florine: a workflow dedicated to nonribosomal peptide discovery.antiSMASH 2.0--a versatile platform for genome mining of secondary metabolite producers.
P2860
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P2860
Comprehensive analysis of distinctive polyketide and nonribosomal peptide structural motifs encoded in microbial genomes.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Comprehensive analysis of dist ...... encoded in microbial genomes.
@en
Comprehensive analysis of dist ...... encoded in microbial genomes.
@nl
type
label
Comprehensive analysis of dist ...... encoded in microbial genomes.
@en
Comprehensive analysis of dist ...... encoded in microbial genomes.
@nl
prefLabel
Comprehensive analysis of dist ...... encoded in microbial genomes.
@en
Comprehensive analysis of dist ...... encoded in microbial genomes.
@nl
P2093
P1476
Comprehensive analysis of dist ...... encoded in microbial genomes.
@en
P2093
Michihiro Araki
Minoru Kanehisa
Yohsuke Minowa
P304
P356
10.1016/J.JMB.2007.02.099
P407
P577
2007-03-14T00:00:00Z