Mathematical models of protein kinase signal transduction.
about
Protein-tyrosine phosphatase 1B modulates early endosome fusion and trafficking of Met and epidermal growth factor receptorsStochastic amplification and signaling in enzymatic futile cycles through noise-induced bistability with oscillationsOpen cascades as simple solutions to providing ultrasensitivity and adaptation in cellular signalingCullin 5 regulates Dab1 protein levels and neuron positioning during cortical developmentSignaling switches and bistability arising from multisite phosphorylation in protein kinase cascadesThe roles of APC and Axin derived from experimental and theoretical analysis of the Wnt pathwaySystems biology approaches in cell signaling researchConfining domains lead to reaction bursts: reaction kinetics in the plasma membraneOperating regimes of signaling cycles: statics, dynamics, and noise filteringA hidden feedback in signaling cascades is revealedCumulative signal transmission in nonlinear reaction-diffusion networksSystematically studying kinase inhibitor induced signaling network signatures by integrating both therapeutic and side effectsExploiting the dynamic properties of covalent modification cycle for the design of synthetic analog biomolecular circuitryThe pseudophosphatase MK-STYX interacts with G3BP and decreases stress granule formationProfiling Subcellular Protein Phosphatase Responses to Coxsackievirus B3 Infection of Cardiomyocytes.A high-throughput assay for phosphoprotein-specific phosphatase activity in cellular extracts.A dynamic analysis of IRS-PKR signaling in liver cells: a discrete modeling approach.Ground state robustness as an evolutionary design principle in signaling networks.Mathematical modeling of intracellular signaling pathways.Topological analysis of MAPK cascade for kinetic ErbB signaling.Sensing and integration of Erk and PI3K signals by MycRegulation of signal duration and the statistical dynamics of kinase activation by scaffold proteins.Cellular phosphatases facilitate combinatorial processing of receptor-activated signalsSignal duration and the time scale dependence of signal integration in biochemical pathways.Input-output behavior of ErbB signaling pathways as revealed by a mass action model trained against dynamic dataSignaling cascades modulate the speed of signal propagation through space.Simple molecular networks that respond optimally to time-periodic stimulation.Positional information generated by spatially distributed signaling cascades.TIde: a software for the systematic scanning of drug targets in kinetic network models.Spatio-temporal correlations can drastically change the response of a MAPK pathwayModeling species-specific diacylglycerol dynamics in the RAW 264.7 macrophage.Theoretical and experimental analysis links isoform-specific ERK signalling to cell fate decisionsUltrasensitive responses and specificity in cell signalingCombining theoretical analysis and experimental data generation reveals IRF9 as a crucial factor for accelerating interferon α-induced early antiviral signalling.Formation of intracellular concentration landscapes by multisite protein modification.The role of dynamic stimulation pattern in the analysis of bistable intracellular networksUnderstanding the temporal codes of intra-cellular signals.Mathematical model of the spatio-temporal dynamics of second messengers in visual transduction.Frequency encoding of T-cell receptor engagement dynamics in calcium time series.Protein scaffolds can enhance the bistability of multisite phosphorylation systems.
P2860
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P2860
Mathematical models of protein kinase signal transduction.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Mathematical models of protein kinase signal transduction.
@en
Mathematical models of protein kinase signal transduction.
@nl
type
label
Mathematical models of protein kinase signal transduction.
@en
Mathematical models of protein kinase signal transduction.
@nl
prefLabel
Mathematical models of protein kinase signal transduction.
@en
Mathematical models of protein kinase signal transduction.
@nl
P2093
P1433
P1476
Mathematical models of protein kinase signal transduction.
@en
P2093
Benjamin G Neel
Reinhart Heinrich
Tom A Rapoport
P304
P356
10.1016/S1097-2765(02)00528-2
P577
2002-05-01T00:00:00Z