IL-15 augments CD8+ T cell-mediated immunity against Toxoplasma gondii infection in mice.
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Differential roles of interleukin 15 mRNA isoforms generated by alternative splicing in immune responses in vivoTreatment with soluble interleukin-15Ralpha exacerbates intracellular parasitic infection by blocking the development of memory CD8+ T cell responseInterleukin-15 may be responsible for early activation of intestinal intraepithelial lymphocytes after oral infection with Listeria monocytogenes in rats.Blimp-1-mediated CD4 T cell exhaustion causes CD8 T cell dysfunction during chronic toxoplasmosis.A simple method to detect Toxoplasma gondii-specific cytotoxic T cells in vivo.Absence of both IL-7 and IL-15 severely impairs the development of CD8 T cell response against Toxoplasma gondii.A dichotomous role for nitric oxide during acute Toxoplasma gondii infection in miceInterleukin-15 augments superoxide production and microbicidal activity of human monocytes against Candida albicans.Combined IL-15/IL-15Ralpha immunotherapy maximizes IL-15 activity in vivo.Interleukin-15 enhances innate and adaptive immune responses to blood-stage malaria infection in mice.Induction of Mycobacterium tuberculosis-specific primary and secondary T-cell responses in interleukin-15-deficient mice.Localized multigene expression patterns support an evolving Th1/Th2-like paradigm in response to infections with Toxoplasma gondii and Ascaris suum.Immune CD8(+) T cells prevent reactivation of Toxoplasma gondii infection in the immunocompromised host.CD8(+)-T-cell immunity against Toxoplasma gondii can be induced but not maintained in mice lacking conventional CD4(+) T cellsImmune response to Encephalitozoon cuniculi infection.Modulation of the host Th1 immune response in pigeon protozoal encephalitis caused by Sarcocystis calchasi.Lack of IL-15 results in the suboptimal priming of CD4+ T cell response against an intracellular parasite.The immunology of parasite infections in immunocompromised hosts.CD8 T Cells and Toxoplasma gondii: A New ParadigmDysregulation of IL-15-mediated T-cell homeostasis in TGF-beta dominant-negative receptor transgenic mice.PD-1-mediated attrition of polyfunctional memory CD8+ T cells in chronic toxoplasma infectionInterleukin-15 increases vaccine efficacy through a mechanism linked to dendritic cell maturation and enhanced antibody titersCoinfection with Heligmosomoides polygyrus fails to establish CD8+ T-cell immunity against Toxoplasma gondiiIL-7 and IL-15 differentially regulate CD8+ T-cell subsets during contraction of the immune response.Donor CD8+ T cells prevent Toxoplasma gondii de-encystation but fail to rescue the exhausted endogenous CD8+ T cell population.IL-7 and IL-15 do not synergize during CD8 T cell recall response against an obligate intracellular parasite.Interleukin-15-deficient mice develop protective immunity to Toxoplasma gondii.The effect of interleukin-15 on the expression of killer-cell immunoglobulin-like receptors on peripheral natural killer cells in human.IL-15 links TLR2/1-induced macrophage differentiation to the vitamin D-dependent antimicrobial pathway.Temporary restoration of immune response against Toxoplasma gondii in HIV-infected individuals after HAART, as studied in the hu-PBMC-SCID mouse model.Downregulated IL-21 Response and T Follicular Helper Cell Exhaustion Correlate with Compromised CD8 T Cell Immunity during Chronic Toxoplasmosis.Immune response and protective effect against chronic Toxoplasma gondii infection induced by vaccination with a DNA vaccine encoding profilin.
P2860
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P2860
IL-15 augments CD8+ T cell-mediated immunity against Toxoplasma gondii infection in mice.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh-hant
name
IL-15 augments CD8+ T cell-mediated immunity against Toxoplasma gondii infection in mice.
@en
IL-15 augments CD8+ T cell-mediated immunity against Toxoplasma gondii infection in mice.
@nl
type
label
IL-15 augments CD8+ T cell-mediated immunity against Toxoplasma gondii infection in mice.
@en
IL-15 augments CD8+ T cell-mediated immunity against Toxoplasma gondii infection in mice.
@nl
prefLabel
IL-15 augments CD8+ T cell-mediated immunity against Toxoplasma gondii infection in mice.
@en
IL-15 augments CD8+ T cell-mediated immunity against Toxoplasma gondii infection in mice.
@nl
P1476
IL-15 augments CD8+ T cell-mediated immunity against Toxoplasma gondii infection in mice.
@en
P2093
P304
P407
P577
1996-09-01T00:00:00Z