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Emerging opportunities for serotypes of botulinum neurotoxinsmiR-153 regulates SNAP-25, synaptic transmission, and neuronal developmentBotulinum neurotoxins A and E undergo retrograde axonal transport in primary motor neuronsNovel Ganglioside-mediated Entry of Botulinum Neurotoxin Serotype D into NeuronsBotulinum neurotoxin serotype A specific cell-based potency assay to replace the mouse bioassayProconvulsant actions of intrahippocampal botulinum neurotoxin B in the rat.Dance of the SNAREs: assembly and rearrangements detected with FRET at neuronal synapses.Botulinum neurotoxin devoid of receptor binding domain translocates active protease.An efficient drug delivery vehicle for botulism countermeasureLipid and cationic polymer based transduction of botulinum holotoxin, or toxin protease alone, extends the target cell range and improves the efficiency of intoxicationTherapeutic use of botulinum toxin in migraine: mechanisms of action.Presynaptic enzymatic neurotoxins.Sensitive and quantitative detection of botulinum neurotoxin in neurons derived from mouse embryonic stem cells.Botulinum neurotoxin subtype A2 enters neuronal cells faster than subtype A1Botulinum neurotoxin type A is internalized and translocated from small synaptic vesicles at the neuromuscular junction.Identification of fibroblast growth factor receptor 3 (FGFR3) as a protein receptor for botulinum neurotoxin serotype A (BoNT/A).Embryonic stem cell-derived motoneurons provide a highly sensitive cell culture model for botulinum neurotoxin studies, with implications for high-throughput drug discoveryTwo synaptobrevin molecules are sufficient for vesicle fusion in central nervous system synapses.Analysis of gene expression in induced pluripotent stem cell-derived human neurons exposed to botulinum neurotoxin A subtype 1 and a type A atoxic derivativeTowards new uses of botulinum toxin as a novel therapeutic toolReceptor binding enables botulinum neurotoxin B to sense low pH for translocation channel assembly.SRC family kinase inhibitors antagonize the toxicity of multiple serotypes of botulinum neurotoxin in human embryonic stem cell-derived motor neuronsBotulinum Neurotoxins Can Enter Cultured Neurons Independent of Synaptic Vesicle RecyclingA Heterologous Reporter Defines the Role of the Tetanus Toxin Interchain Disulfide in Light-Chain TranslocationRecent developments in cell-based assays and stem cell technologies for botulinum neurotoxin research and drug discoveryNovel application of human neurons derived from induced pluripotent stem cells for highly sensitive botulinum neurotoxin detectionBotulinum neurotoxins B and E translocate at different rates and exhibit divergent responses to GT1b and low pHA Novel Inhibitor Prevents the Peripheral Neuroparalysis of Botulinum Neurotoxins.Use of a recombinant fluorescent substrate with cleavage sites for all botulinum neurotoxins in high-throughput screening of natural product extracts for inhibitors of serotypes A, B, and E.A role for soluble N-ethylmaleimide-sensitive factor attachment protein receptor complex dimerization during neurosecretion.Progress in cell based assays for botulinum neurotoxin detectionBotulism diagnostics: from clinical symptoms to in vitro assays.Glycosylated SV2A and SV2B mediate the entry of botulinum neurotoxin E into neurons.Bimodal modulation of the botulinum neurotoxin protein-conducting channelCharacterization of botulinum neurotoxin A subtypes 1 through 5 by investigation of activities in mice, in neuronal cell cultures, and in vitro.A neuronal cell-based botulinum neurotoxin assay for highly sensitive and specific detection of neutralizing serum antibodies.Receptor and substrate interactions of clostridial neurotoxins.Targeted secretion inhibitors-innovative protein therapeuticsBotulinum neurotoxin for pain management: insights from animal models.SNARE requirements en route to exocytosis: from many to few.
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
Uptake of botulinum neurotoxin into cultured neurons.
@en
Uptake of botulinum neurotoxin into cultured neurons.
@nl
type
label
Uptake of botulinum neurotoxin into cultured neurons.
@en
Uptake of botulinum neurotoxin into cultured neurons.
@nl
prefLabel
Uptake of botulinum neurotoxin into cultured neurons.
@en
Uptake of botulinum neurotoxin into cultured neurons.
@nl
P2093
P356
P1433
P1476
Uptake of botulinum neurotoxin into cultured neurons.
@en
P2093
Elaine A Neale
James E Keller
P304
P356
10.1021/BI0356698
P407
P577
2004-01-01T00:00:00Z