about
The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetesSox6 is necessary for efficient erythropoiesis in adult mice under physiological and anemia-induced stress conditionsSOX9 is required for maintenance of the pancreatic progenitor cell poolControl of endodermal endocrine development by Hes-1Pax6 and Pdx1 form a functional complex on the rat somatostatin gene upstream enhancerTranscription factor hepatocyte nuclear factor 6 regulates pancreatic endocrine cell differentiation and controls expression of the proendocrine gene ngn3Activated Notch1 prevents differentiation of pancreatic acinar cells and attenuate endocrine developmentFGF10 signaling maintains the pancreatic progenitor cell state revealing a novel role of Notch in organ developmentFGF10 maintains distal lung bud epithelium and excessive signaling leads to progenitor state arrest, distalization, and goblet cell metaplasia.Isolation and characterization of centroacinar/terminal ductal progenitor cells in adult mouse pancreasGene regulatory factors in pancreatic development.Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium.GeneSpeed: protein domain organization of the transcriptomeFGF10 signaling controls stomach morphogenesis.Notch-mediated patterning and cell fate allocation of pancreatic progenitor cells.SEC23B is required for the maintenance of murine professional secretory tissues.Glis3 regulates neurogenin 3 expression in pancreatic β-cells and interacts with its activator, Hnf6.The development of diabetes in E2f1/E2f2 mutant mice reveals important roles for bone marrow-derived cells in preventing islet cell loss.A far-upstream (-70 kb) enhancer mediates Sox9 auto-regulation in somatic tissues during development and adult regeneration.Mouse pancreatic endocrine cell transcriptome defined in the embryonic Ngn3-null mouse.Pathway decision-making strategies for generating pancreatic beta-cells: systems biology or hit and miss?Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression.Exocrine ontogenies: on the development of pancreatic acinar, ductal and centroacinar cellsNotch signaling in the pancreas: patterning and cell fate specification.Pancreatic islet and progenitor cell surface markers with cell sorting potential.Polyswitch lentivectors: "all-in-one" lentiviral vectors for drug-inducible gene expression, live selection, and recombination cloning.Conditional control of the differentiation competence of pancreatic endocrine and ductal cells by Fgf10.Pax4 represses pancreatic glucagon gene expression.Hedgehog signaling is required for effective regeneration of exocrine pancreas.Pax6 and Cdx2/3 form a functional complex on the rat glucagon gene promoter G1-element.Fibroblast growth factor 10 represses premature cell differentiation during establishment of the intestinal progenitor niche.Expression and misexpression of members of the FGF and TGFbeta families of growth factors in the developing mouse pancreas.Global gene expression profiling and histochemical analysis of the developing human fetal pancreas.Recapitulation of elements of embryonic development in adult mouse pancreatic regeneration.Islet expression of Rhombotin and Isl-1 suggests cell type specific exposure of LIM-domain epitopes.Molecular mapping of the origin of postnatal spinal cord ependymal cells: evidence that adult ependymal cells are derived from Nkx6.1+ ventral neural progenitor cells.Notch-mediated post-translational control of Ngn3 protein stability regulates pancreatic patterning and cell fate commitment.ETS-family genes in pancreatic development.Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation.Evidence for the differential regulation of Nkx-6.1 expression in the ventral spinal cord and foregut by Shh-dependent and -independent mechanisms.
P50
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Jan Jensen
@ast
Jan Jensen
@en
Jan Jensen
@es
Jan Jensen
@nl
Jan Jensen
@sl
type
label
Jan Jensen
@ast
Jan Jensen
@en
Jan Jensen
@es
Jan Jensen
@nl
Jan Jensen
@sl
prefLabel
Jan Jensen
@ast
Jan Jensen
@en
Jan Jensen
@es
Jan Jensen
@nl
Jan Jensen
@sl
P106
P1153
55315591600
P2456
P31
P496
0000-0003-0657-4032