Fourth-generation model for corticosteroid pharmacodynamics: a model for methylprednisolone effects on receptor/gene-mediated glucocorticoid receptor down-regulation and tyrosine aminotransferase induction in rat liver.
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In silico simulation of corticosteroids effect on an NFkB- dependent physicochemical model of systemic inflammationMeta-modeling of methylprednisolone effects on glucose regulation in ratsModeling circadian rhythms of glucocorticoid receptor and glutamine synthetase expression in rat skeletal muscleThe genomic response of skeletal muscle to methylprednisolone using microarrays: tailoring data mining to the structure of the pharmacogenomic time series.Corticosteroid-regulated genes in rat kidney: mining time series array data.Application of scaling factors in simultaneous modeling of microarray data from diverse chips.Comparative analysis of acute and chronic corticosteroid pharmacogenomic effects in rat liver: transcriptional dynamics and regulatory structures.Modeling receptor/gene-mediated effects of corticosteroids on hepatic tyrosine aminotransferase dynamics in rats: dual regulation by endogenous and exogenous corticosteroids.Pharmacokinetics of methylprednisolone after intravenous and intramuscular administration in rats.A microarray analysis of the temporal response of liver to methylprednisolone: a comparative analysis of two dosing regimens.Assessing the dynamics of nuclear glucocorticoid-receptor complex: adding flexibility to gene expression modeling.Microarray analysis of the temporal response of skeletal muscle to methylprednisolone: comparative analysis of two dosing regimens.Mathematical modeling of corticosteroid pharmacogenomics in rat muscle following acute and chronic methylprednisolone dosingModeling of corticosteroid effects on hepatic low-density lipoprotein receptors and plasma lipid dynamics in ratsGene arrays and temporal patterns of drug response: corticosteroid effects on rat liver.Fifth-generation model for corticosteroid pharmacodynamics: application to steady-state receptor down-regulation and enzyme induction patterns during seven-day continuous infusion of methylprednisolone in rats.Quantitative tissue-specific dynamics of in vivo GILZ mRNA expression and regulation by endogenous and exogenous glucocorticoids.Modeling autonomic regulation of cardiac function and heart rate variability in human endotoxemia.Applications of quantitative pharmacodynamic effect markers in drug target identification and therapy developmentTemporal profiling of the transcriptional basis for the development of corticosteroid-induced insulin resistance in rat muscle.Modeling corticosteroid effects in a rat model of rheumatoid arthritis I: mechanistic disease progression model for the time course of collagen-induced arthritis in Lewis rats.Pharmacodynamics of glucose regulation by methylprednisolone. I. Adrenalectomized rats.Pharmacogenomic responses of rat liver to methylprednisolone: an approach to mining a rich microarray time seriesPharmacodynamic/pharmacogenomic modeling of insulin resistance genes in rat muscle after methylprednisolone treatment: exploring regulatory signaling cascades.Pharmacodynamic modeling of acute and chronic effects of methylprednisolone on hepatic urea cycle genes in rats.A stochastic version of corticosteriod pharmacogenomic model.Tissue-specific gene expression and regulation in liver and muscle following chronic corticosteroid administration.Understanding Physiology in the Continuum: Integration of Information from Multiple -Omics Levels.Lifespan based indirect response models.NETWORKS, BIOLOGY AND SYSTEMS ENGINEERING: A CASE STUDY IN INFLAMMATION.Pharmacometrics: modelling and simulation tools to improve decision making in clinical drug development.
P2860
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P2860
Fourth-generation model for corticosteroid pharmacodynamics: a model for methylprednisolone effects on receptor/gene-mediated glucocorticoid receptor down-regulation and tyrosine aminotransferase induction in rat liver.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
Fourth-generation model for co ...... ferase induction in rat liver.
@en
Fourth-generation model for co ...... ferase induction in rat liver.
@nl
type
label
Fourth-generation model for co ...... ferase induction in rat liver.
@en
Fourth-generation model for co ...... ferase induction in rat liver.
@nl
prefLabel
Fourth-generation model for co ...... ferase induction in rat liver.
@en
Fourth-generation model for co ...... ferase induction in rat liver.
@nl
P2093
P356
P1476
Fourth-generation model for co ...... ferase induction in rat liver.
@en
P2093
P2888
P304
P356
10.1023/A:1023233409550
P577
1998-06-01T00:00:00Z
P6179
1021162219