Discovery of Tirasemtiv, the First Direct Fast Skeletal Muscle Troponin Activator.

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Discovery of Tirasemtiv, the First Direct Fast Skeletal Muscle Troponin Activator.

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2018 nî lūn-bûn

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2018年の論文

@ja

2018年学术文章

@wuu

2018年学术文章

@zh

2018年学术文章

@zh-cn

2018年学术文章

@zh-hans

2018年学术文章

@zh-my

2018年学术文章

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2018年學術文章

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2018年學術文章

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Discovery of Tirasemtiv, the First Direct Fast Skeletal Muscle Troponin Activator.

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Discovery of Tirasemtiv, the First Direct Fast Skeletal Muscle Troponin Activator.

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Item

label

Discovery of Tirasemtiv, the First Direct Fast Skeletal Muscle Troponin Activator.

@en

Discovery of Tirasemtiv, the First Direct Fast Skeletal Muscle Troponin Activator.

@nl

prefLabel

Discovery of Tirasemtiv, the First Direct Fast Skeletal Muscle Troponin Activator.

@en

Discovery of Tirasemtiv, the First Direct Fast Skeletal Muscle Troponin Activator.

@nl

P1476

Discovery of Tirasemtiv, the First Direct Fast Skeletal Muscle Troponin Activator

@en

P2093

Aaron C Hinken

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Adam Kennedy

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Alexander Muci

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Bradley P Morgan

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Darren Hwee

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David J Morgans

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David Marquez

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Donghong Xu

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Fady I Malik

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Gustave Bergnes

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P2860

A study to evaluate safety and tolerability of repeated doses of tirasemtiv in patients with amyotrophic lateral sclerosis

Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseases

Ligand efficiency: a useful metric for lead selection

Amyotrophic lateral sclerosis

Prediction of human clearance of twenty-nine drugs from hepatic microsomal intrinsic clearance data: An examination of in vitro half-life approach and nonspecific binding to microsomes.

Cardiac myosin activation: a potential therapeutic approach for systolic heart failure.

Fast skeletal muscle troponin activator tirasemtiv increases muscle function and performance in the B6SJL-SOD1G93A ALS mouse model

The role of troponins in muscle contraction.

Effects of high- and low-velocity resistance training on the contractile properties of skeletal muscle fibers from young and older humans

Update on Charcot-Marie-Tooth disease.

P304

354-358

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P31

scholarly article

P356

10.1021/ACSMEDCHEMLETT.7B00546

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P433

http://www.w3.org/2001/XMLSchema#string

P478

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P50

Alan J Russell

Scott E Collibee

P577

2018-02-13T00:00:00Z

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P698

29670700

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P932

5900333

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