Structurally-Related Kappa Opioid Receptor Agonists with Substantial Differential Signaling Bias: Neuroendocrine and Behavioral Effects in C57BL6 Mice.

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Structurally-Related Kappa Opioid Receptor Agonists with Substantial Differential Signaling Bias: Neuroendocrine and Behavioral Effects in C57BL6 Mice.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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Structurally-Related Kappa Opi ...... vioral Effects in C57BL6 Mice.

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Structurally-Related Kappa Opi ...... vioral Effects in C57BL6 Mice.

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label

Structurally-Related Kappa Opi ...... vioral Effects in C57BL6 Mice.

@en

Structurally-Related Kappa Opi ...... vioral Effects in C57BL6 Mice.

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Structurally-Related Kappa Opi ...... vioral Effects in C57BL6 Mice.

@en

Structurally-Related Kappa Opi ...... vioral Effects in C57BL6 Mice.

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P1476

Structurally-Related Kappa Opi ...... vioral Effects in C57BL6 Mice.

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P2093

Alexandra M Dunn

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Amelia D Dunn

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Brian Reed

http://www.w3.org/2001/XMLSchema#string

Catherine Guariglia

http://www.w3.org/2001/XMLSchema#string

Joshua M Hillman

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P2860

Kappa opioids promote the proliferation of astrocytes via Gbetagamma and beta-arrestin 2-dependent MAPK-mediated pathways

Role of kappa-opioid receptors in stress and anxiety-related behavior.

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

U69593, a kappa-opioid agonist, decreases cocaine self-administration and decreases cocaine-produced drug-seeking

The G protein-biased κ-opioid receptor agonist RB-64 is analgesic with a unique spectrum of activities in vivo

Nalmefene induced elevation in serum prolactin in normal human volunteers: partial kappa opioid agonist activity?

Differential effects of the novel kappa opioid receptor antagonist, JDTic, on reinstatement of cocaine-seeking induced by footshock stressors vs cocaine primes and its antidepressant-like effects in rats

Discovery and pharmacological evaluation of a diphenethylamine derivative (HS665), a highly potent and selective κ opioid receptor agonist

A simple method for quantifying functional selectivity and agonist bias

Selective κ receptor partial agonist HS666 produces potent antinociception without inducing aversion after i.c.v. administration in mice.

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scholarly article

P356

10.1093/IJNP/PYY034

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P50

Mary Jeanne Kreek

P577

2018-04-04T00:00:00Z

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P698

29635340

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P921

bias

P932

6119295

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