On the tertiary structure of the extracellular domains of the epidermal growth factor and insulin receptors.
about
The relationship between the L1 and L2 domains of the insulin and epidermal growth factor receptors and leucine-rich repeat modulesThe Chlamydia pneumoniae invasin protein Pmp21 recruits the EGF receptor for host cell entryCrystal structure of the first three domains of the type-1 insulin-like growth factor receptorReceptor tyrosine kinase signaling: regulating neural crest development one phosphate at a timeDecorin binds to a narrow region of the epidermal growth factor (EGF) receptor, partially overlapping but distinct from the EGF-binding epitopeThe three dimensional structure of the type I insulin-like growth factor receptor.Solenoid and non-solenoid protein recognition using stationary wavelet packet transform.Disulfide bond structure of human epidermal growth factor receptor.Insulin and its receptor: structure, function and evolution.A comparative structural bioinformatics analysis of the insulin receptor family ectodomain based on phylogenetic information.Five mutant alleles of the insulin receptor gene in patients with genetic forms of insulin resistance.The tethering arm of the EGF receptor is required for negative cooperativity and signal transduction.Muc4-ErbB2 complex formation and signaling in polarized CACO-2 epithelial cells indicate that Muc4 acts as an unorthodox ligand for ErbB2Structure and evolution of insulins: implications for receptor binding.Activation of glucose transport by a natural mutation in the human insulin receptorStructural insights into ligand-induced activation of the insulin receptor.Mutations in the polybasic juxtamembrane sequence of both plasma membrane- and endoplasmic reticulum-localized epidermal growth factor receptors confer ligand-independent cell transformation.Targeting the epidermal growth factor receptor in solid tumor malignancies.The insulin receptor changes conformation in unforeseen ways on ligand binding: sharpening the picture of insulin receptor activation.Functional reconstitution of insulin receptor binding site from non-binding receptor fragments.Replacements of leucine 87 in human insulin receptor alter affinity for insulin.Dimeric fragment of the insulin receptor alpha-subunit binds insulin with full holoreceptor affinity.Cysteine-524 is not the only residue involved in the formation of disulphide-bonded dimers of the insulin receptorExpression and characterization of a 70-kDa fragment of the insulin receptor that binds insulin. Minimizing ligand binding domain of the insulin receptor.Epidermal growth factor binding induces a conformational change in the external domain of its receptor.Analysis of the glycosylation patterns of the extracellular domain of the epidermal growth factor receptor expressed in Chinese hamster ovary fibroblasts.Anti-EGFR Agents: Current Status, Forecasts and Future Directions.Mutational analysis of the N-linked glycosylation sites of the human insulin receptorDo specific interactions between transmembrane helices play a part in signalling transduction? Exploration with the insulin receptor.Congenital insulin resistance associated with a conformational alteration in a conserved beta-sheet in the insulin receptor L1 domain.Mapping of an NH2-terminal ligand binding site of the insulin receptor by alanine scanning mutagenesis.Structural studies of the detergent-solubilized and vesicle-reconstituted insulin receptor.Sulphydryl agents modulate insulin- and epidermal growth factor (EGF)-receptor kinase via reaction with intracellular receptor domains: differential effects on basal versus activated receptors.Polymorphism of the epidermal growth factor receptor extracellular ligand binding domain: the dimer interface depends on domain stabilization.Structural determinants of the insulin receptor-related receptor activation by alkali.The membrane proximal disulfides of the EGF receptor extracellular domain are required for high affinity binding and signal transduction but do not play a role in the localization of the receptor to lipid rafts.Crystallization of the first three domains of the human insulin-like growth factor-1 receptor.Characterization of a comparative model of the extracellular domain of the epidermal growth factor receptorHormone-triggered conformational changes within the insulin-receptor ectodomain: requirement for transmembrane anchors.Alanine scanning mutagenesis of a type 1 insulin-like growth factor receptor ligand binding site.
P2860
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P2860
On the tertiary structure of the extracellular domains of the epidermal growth factor and insulin receptors.
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年学术文章
@wuu
1987年学术文章
@zh
1987年学术文章
@zh-cn
1987年学术文章
@zh-hans
1987年学术文章
@zh-my
1987年学术文章
@zh-sg
1987年學術文章
@yue
1987年學術文章
@zh-hant
name
On the tertiary structure of t ...... factor and insulin receptors.
@en
On the tertiary structure of t ...... factor and insulin receptors.
@nl
type
label
On the tertiary structure of t ...... factor and insulin receptors.
@en
On the tertiary structure of t ...... factor and insulin receptors.
@nl
prefLabel
On the tertiary structure of t ...... factor and insulin receptors.
@en
On the tertiary structure of t ...... factor and insulin receptors.
@nl
P2093
P1476
On the tertiary structure of t ...... factor and insulin receptors.
@en
P2093
J Schlessinger
M D Waterfield
W R Taylor
P304
P356
10.1016/0167-4838(87)90112-9
P50
P577
1987-11-01T00:00:00Z