Designed disulfide between N-terminal domains of lactose repressor disrupts allosteric linkage.
about
A designed redox-controlled caspaseAmino acid positions subject to multiple coevolutionary constraints can be robustly identified by their eigenvector network centrality scoresData on publications, structural analyses, and queries used to build and utilize the AlloRep database.Strong DNA binding by covalently linked dimeric Lac headpiece: evidence for the crucial role of the hinge helices.Fine-tuning function: correlation of hinge domain interactions with functional distinctions between LacI and PurRExtrinsic interactions dominate helical propensity in coupled binding and folding of the lactose repressor protein hinge helix.Lactose Repressor Hinge Domain Independently Binds DNA.
P2860
Q27670443-8163FB2F-A7C5-4D62-B414-604818317113Q30380675-640B5B4D-B286-485F-B1E7-D1B485327DB7Q31120856-B61DDD9E-1F39-4361-841A-8DDF57821852Q35926930-821A5A1D-1F0C-4782-B7CA-2A60F56DB29AQ36639184-5311D3B9-185C-43C7-9024-6AA8F02E5E8BQ37239949-EEDDA1F7-E02B-4BD8-8E1D-D4FC1206FC82Q47214879-38EFA162-CF6A-43F9-8964-70574128D430
P2860
Designed disulfide between N-terminal domains of lactose repressor disrupts allosteric linkage.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh-hant
name
Designed disulfide between N-t ...... r disrupts allosteric linkage.
@en
Designed disulfide between N-t ...... r disrupts allosteric linkage.
@nl
type
label
Designed disulfide between N-t ...... r disrupts allosteric linkage.
@en
Designed disulfide between N-t ...... r disrupts allosteric linkage.
@nl
prefLabel
Designed disulfide between N-t ...... r disrupts allosteric linkage.
@en
Designed disulfide between N-t ...... r disrupts allosteric linkage.
@nl
P2860
P356
P1476
Designed disulfide between N-t ...... r disrupts allosteric linkage.
@en
P2093
Matthews KS
P2860
P304
26818-26821
P356
10.1074/JBC.272.43.26818
P407
P577
1997-10-01T00:00:00Z