Design, Synthesis, and Characterization of Brequinar Conjugates as Probes to Study DHODH Inhibition.

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Design, Synthesis, and Characterization of Brequinar Conjugates as Probes to Study DHODH Inhibition.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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Design, Synthesis, and Charact ...... bes to Study DHODH Inhibition.

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Design, Synthesis, and Charact ...... bes to Study DHODH Inhibition.

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Design, Synthesis, and Charact ...... bes to Study DHODH Inhibition.

@en

Design, Synthesis, and Charact ...... bes to Study DHODH Inhibition.

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Design, Synthesis, and Charact ...... bes to Study DHODH Inhibition.

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Design, Synthesis, and Charact ...... bes to Study DHODH Inhibition.

@nl

P1476

Design, Synthesis, and Charact ...... bes to Study DHODH Inhibition.

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P2093

Christine R Cuthbertson

http://www.w3.org/2001/XMLSchema#string

Joseph T Madak

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Nouri Neamati

http://www.w3.org/2001/XMLSchema#string

Wenmin Chen

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P2860

Structures of human dihydroorotate dehydrogenase in complex with antiproliferative agents

Structure-Guided Design and Optimization of Small Molecules Targeting the Protein–Protein Interaction between the von Hippel–Lindau (VHL) E3 Ubiquitin Ligase and the Hypoxia Inducible Factor (HIF) Alpha Subunit with in Vitro Nanomolar Affinities

Small-Molecule Inhibitors of the Interaction between the E3 Ligase VHL and HIF1α

On dihydroorotate dehydrogenases and their inhibitors and uses

Degradation of an intramitochondrial protein by the cytosolic proteasome

Recent developments in the medicinal chemistry and therapeutic potential of dihydroorotate dehydrogenase (DHODH) inhibitors.

HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins.

Induced protein degradation: an emerging drug discovery paradigm.

Small-Molecule PROTACS: New Approaches to Protein Degradation.

Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia.

P304

13875-13878

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P31

scholarly article

P356

10.1002/CHEM.201702999

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P407

English

P433

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P478

http://www.w3.org/2001/XMLSchema#string

P50

Hollis D Showalter

P577

2017-08-21T00:00:00Z

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P698

28833638

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