Structural determinants of the ligand-binding site of the human retinoic acid receptor alpha.

Structural determinants of the ligand-binding site of the human retinoic acid receptor alpha.

Item
http://www.wikidata.org/entity/Q52538819
Retinoic acid receptors inhibit AP1 activation by regulating extracellular signal-regulated kinase and CBP recruitment to an AP1-responsive promoter.Selective alteration of gene expression in response to natural and synthetic retinoidsThe proliferating cell nuclear antigen regulates retinoic acid receptor transcriptional activity through direct protein-protein interaction.Allosteric regulation of the discriminative responsiveness of retinoic acid receptor to natural and synthetic ligands by retinoid X receptor and DNA.Chromosomal integration of retinoic acid response elements prevents cooperative transcriptional activation by retinoic acid receptor and retinoid X receptor.Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gammaMutational analysis reveals that all-trans-retinoic acid, 9-cis-retinoic acid, and antagonist interact with distinct binding determinants of RARalpha.Analysis of the ligand-binding domain of human retinoic acid receptor alpha by site-directed mutagenesis.Modular structure of glucocorticoid receptor domains is not equivalent to functional independence. Stability and activity of the steroid binding domain are controlled by sequences in separate domains.Retinoid X receptor alpha (RXRalpha) helix 12 plays an inhibitory role in the recruitment of the p160 co-activators by unliganded RXRalpha/retinoic acid receptor alpha heterodimers.
P2860

Structural determinants of the ligand-binding site of the human retinoic acid receptor alpha.

Item
http://www.wikidata.org/entity/Q52538819
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name
Structural determinants of the ...... retinoic acid receptor alpha.
@en
Structural determinants of the ...... retinoic acid receptor alpha.
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Structural determinants of the ...... retinoic acid receptor alpha.
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Structural determinants of the ...... retinoic acid receptor alpha.
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Structural determinants of the ...... retinoic acid receptor alpha.
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Structural determinants of the ...... retinoic acid receptor alpha.
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Structural determinants of the ...... retinoic acid receptor alpha.
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P2093
P304
P31
P356
P407
P433
P478
P577
P698
P921