Gadd45a contributes to p53 stabilization in response to DNA damage. - Wikidata - wikimedia - TriplyDB

Gadd45a contributes to p53 stabilization in response to DNA damage.

Gadd45a contributes to p53 stabilization in response to DNA damage.

http://www.wikidata.org/entity/Q52552558

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GADD45 proteins: central players in tumorigenesis Expression profile of genes regulated by activity of the Na-H exchanger NHE1 Adenosine induces cell-cycle arrest and apoptosis in androgen-dependent and -independent prostate cancer cell lines, LNcap-FGC-10, DU-145, and PC3.Molecular mechanisms of A3 adenosine receptor-induced G1 cell cycle arrest and apoptosis in androgen-dependent and independent prostate cancer cell lines: involvement of intrinsic pathway.Profiles of global gene expression in ionizing-radiation-damaged human diploid fibroblasts reveal synchronization behind the G1 checkpoint in a G0-like state of quiescence.Inhibitor of apoptosis-stimulating protein of p53 (iASPP) is required for neuronal survival after axonal injury.Gadd45a sensitizes medulloblastoma cells to irradiation and suppresses MMP-9-mediated EMT Herbal Extracts Induce Dermal Papilla Cell Proliferation of Human Hair Follicles.Silibinin prevents ultraviolet B radiation-induced epidermal damages in JB6 cells and mouse skin in a p53-GADD45α-dependent manner.Transcriptomic Analysis Implicates the p53 Signaling Pathway in the Establishment of HIV-1 Latency in Central Memory CD4 T Cells in an In Vitro Model.The vitamin D receptor as a therapeutic target.Decitabine-induced demethylation of 5' CpG island in GADD45A leads to apoptosis in osteosarcoma cells.p38 MAPK-induced MDM2 degradation confers paclitaxel resistance through p53-mediated regulation of EGFR in human lung cancer cells.p53 controls hepatitis C virus non-structural protein 5A-mediated downregulation of GADD45α expression via the NF-κB and PI3K-Akt pathways.Non-classical p38 map kinase functions: cell cycle checkpoints and survival.Anti-tumor activity of Eurycoma longifolia root extracts against K-562 cell line: in vitro and in vivo study.Altered SMRT levels disrupt vitamin D3 receptor signalling in prostate cancer cells.Induction of nuclear translocation of mutant cytoplasmic p53 by geranylgeranoic acid in a human hepatoma cell line.The long non-coding RNA GAS5 differentially regulates cell cycle arrest and apoptosis through activation of BRCA1 and p53 in human neuroblastoma.Fisetin, a dietary flavonoid, induces cell cycle arrest and apoptosis through activation of p53 and inhibition of NF-kappa B pathways in bladder cancer cells.Suppression of Gadd45 alleviates the G2/M blockage and the enhanced phosphorylation of p53 and p38 in zinc supplemented normal human bronchial epithelial cells.Infrared radiation induces the p53 signaling pathway: role in infrared prevention of ultraviolet B toxicity.Microarray analyses of otospheres derived from the cochlea in the inner ear identify putative transcription factors that regulate the characteristics of otospheres.GADD45A plays a protective role against temozolomide treatment in glioblastoma cells.Gadd45a regulates beta-catenin distribution and maintains cell-cell adhesion/contact.ERβ alters the chemosensitivity of luminal breast cancer cells by regulating p53 function.

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P2860

Gadd45a contributes to p53 stabilization in response to DNA damage.

http://www.wikidata.org/entity/Q52552558

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

@zh-hans

2003年学术文章

@zh-my

2003年学术文章

@zh-sg

2003年學術文章

@yue

2003年學術文章

@zh-hant

name

Gadd45a contributes to p53 stabilization in response to DNA damage.

@en

Gadd45a contributes to p53 stabilization in response to DNA damage.

@nl

type

label

Gadd45a contributes to p53 stabilization in response to DNA damage.

@en

Gadd45a contributes to p53 stabilization in response to DNA damage.

@nl

prefLabel

Gadd45a contributes to p53 stabilization in response to DNA damage.

@en

Gadd45a contributes to p53 stabilization in response to DNA damage.

@nl

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Gadd45a contributes to p53 stabilization in response to DNA damage.

@en

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Baskaran Rajasekaran

http://www.w3.org/2001/XMLSchema#string

Kimberly L Petrik

http://www.w3.org/2001/XMLSchema#string

Lucia Mazzacurati

http://www.w3.org/2001/XMLSchema#string

Min Wu

http://www.w3.org/2001/XMLSchema#string

Qimin Zhan

http://www.w3.org/2001/XMLSchema#string

Shao Shujuan

http://www.w3.org/2001/XMLSchema#string

Shunqian Jin

http://www.w3.org/2001/XMLSchema#string

Tong Tong

http://www.w3.org/2001/XMLSchema#string

Xiaocheng Zhu

http://www.w3.org/2001/XMLSchema#string

Yongmei Song

http://www.w3.org/2001/XMLSchema#string

P2860

GADD45 induction of a G2/M cell cycle checkpoint

The GADD45 inhibition of Cdc2 kinase correlates with GADD45-mediated growth suppression

The central region of Gadd45 is required for its interaction with p21/WAF1

Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway

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8536-8540

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scholarly article

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10.1038/SJ.ONC.1206907

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52

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22

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2003-11-01T00:00:00Z

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8999604

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14627995

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