Disruption and aberrant expression of HMGA2 as a consequence of diverse chromosomal translocations in myeloid malignancies.
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The tumor suppressor microRNA let-7 represses the HMGA2 oncogene.Transcriptional regulation by targeted expression of architectural transcription factor high mobility group A2 in salivary glands of transgenic miceLet-7 microRNA and HMGA2 levels of expression are not inversely linked in adipocytic tumors: analysis of 56 lipomas and liposarcomas with molecular cytogenetic data.TLX1 and NOTCH coregulate transcription in T cell acute lymphoblastic leukemia cells.Refinement of 1p36 alterations not involving PRDM16 in myeloid and lymphoid malignanciesFine mapping of 14q24.1 breast cancer susceptibility locusSite-specific gene insertion mediated by a Cre-loxP-carrying lentiviral vector.Hmga2 is a direct target gene of RUNX1 and regulates expansion of myeloid progenitors in mice.Human HMGA2 protein overexpressed in mice induces precursor T-cell lymphoblastic leukemia3'UTR-truncated Hmga2 cDNA causes MPN-like hematopoiesis by conferring a clonal growth advantage at the level of HSC in mice.The genetics of the myelodysplastic syndromes: classical cytogenetics and recent molecular insights.Overexpression of HMGA2 promotes tongue cancer metastasis through EMT pathwayIdentification of microRNA-regulated pathways using an integration of microRNA-mRNA microarray and bioinformatics analysis in CD34+ cells of myelodysplastic syndromes.Translocations in epithelial cancers.Extramedullary hematopoiesis (EMH) in laboratory animals: offering an insight into stem cell research.Hmga2 promotes the development of myelofibrosis in Jak2V617F knockin mice by enhancing TGF-β1 and Cxcl12 pathways.Function of high-mobility group A proteins in the DNA damage signaling for the induction of apoptosisTransient JAK2 V617F mutation in an aplastic anaemia patient with a paroxysmal nocturnal haemoglobinuria clone.Identification of a novel fusion gene HMGA2-EGFR in glioblastoma.miR-9 is a tumor suppressor in pediatric AML with t(8;21).Silencing of HMGA2 reverses retardance of cell differentiation in human myeloid leukaemia.Quantitative expression analysis in peripheral blood of patients with chronic myeloid leukaemia: correlation between HMGA2 expression and white blood cell count.Dysregulation of the MIRLET7/HMGA2 axis with methylation of the CDKN2A promoter in myeloproliferative neoplasms.t(3;12)(q26;q14) in polycythemia vera is associated with upregulation of the HMGA2 gene
P2860
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P2860
Disruption and aberrant expression of HMGA2 as a consequence of diverse chromosomal translocations in myeloid malignancies.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
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2005年學術文章
@zh-hant
name
Disruption and aberrant expres ...... tions in myeloid malignancies.
@en
Disruption and aberrant expres ...... tions in myeloid malignancies.
@nl
type
label
Disruption and aberrant expres ...... tions in myeloid malignancies.
@en
Disruption and aberrant expres ...... tions in myeloid malignancies.
@nl
prefLabel
Disruption and aberrant expres ...... tions in myeloid malignancies.
@en
Disruption and aberrant expres ...... tions in myeloid malignancies.
@nl
P2093
P2860
P356
P1433
P1476
Disruption and aberrant expres ...... tions in myeloid malignancies.
@en
P2093
Andrieux J
Calasanz MJ
Vizmanos JL
P2860
P2888
P304
P356
10.1038/SJ.LEU.2403605
P577
2005-02-01T00:00:00Z
P5875
P6179
1048232329