Analysis of oxidative events induced by expanded polyglutamine huntingtin exon 1 that are differentially restored by expression of heat shock proteins or treatment with an antioxidant.
about
Huntington's disease induced cardiac amyloidosis is reversed by modulating protein folding and oxidative stress pathways in the Drosophila heartRole of oxidative DNA damage in mitochondrial dysfunction and Huntington's disease pathogenesisS-glutathionylation: from molecular mechanisms to health outcomesDysregulation of heat shock protein 27 expression in oral tongue squamous cell carcinomaSelective degradation of aggregate-prone CryAB mutants by HSPB1 is mediated by ubiquitin-proteasome pathwaysDithiol-based compounds maintain expression of antioxidant protein peroxiredoxin 1 that counteracts toxicity of mutant huntingtin.Blocking the association of HDAC4 with MAP1S accelerates autophagy clearance of mutant Huntingtin.The role of small heat-shock protein αB-crystalline (HspB5) in COPD pathogenesisHsp27 (HspB1) and alphaB-crystallin (HspB5) as therapeutic targets.Novel therapeutic strategies for the treatment of protein-misfolding diseases.S-nitrosylation of dynamin-related protein 1 mediates mutant huntingtin-induced mitochondrial fragmentation and neuronal injury in Huntington's disease.Pathology-dependent effects linked to small heat shock proteins expression: an updateHspB1, HspB5 and HspB4 in Human Cancers: Potent Oncogenic Role of Some of Their Client Proteins.Quercetin improves the activity of the ubiquitin-proteasomal system in 150Q mutated huntingtin-expressing cells but exerts detrimental effects on neuronal survivability.Mammalian HspB1 (Hsp27) is a molecular sensor linked to the physiology and environment of the cell.In vitro and in vivo aggregation of a fragment of huntingtin protein directly causes free radical production.HSP70 interacting protein prevents the accumulation of inclusions in polyglutamine disease.Huntingtin inclusion bodies are iron-dependent centers of oxidative events.Using bicistronic constructs to evaluate the chaperone activities of heat shock proteins in cells.
P2860
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P2860
Analysis of oxidative events induced by expanded polyglutamine huntingtin exon 1 that are differentially restored by expression of heat shock proteins or treatment with an antioxidant.
description
2006 nî lūn-bûn
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2006年の論文
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name
Analysis of oxidative events i ...... treatment with an antioxidant.
@en
Analysis of oxidative events i ...... treatment with an antioxidant.
@nl
type
label
Analysis of oxidative events i ...... treatment with an antioxidant.
@en
Analysis of oxidative events i ...... treatment with an antioxidant.
@nl
prefLabel
Analysis of oxidative events i ...... treatment with an antioxidant.
@en
Analysis of oxidative events i ...... treatment with an antioxidant.
@nl
P2093
P2860
P1433
P1476
Analysis of oxidative events i ...... treatment with an antioxidant.
@en
P2093
Andreas Wyttenbach
André-Patrick Arrigo
Chantal Diaz-Latoud
R W Currie
Wance J J Firdaus
P2860
P304
P356
10.1111/J.1742-4658.2006.05318.X
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P577
2006-07-01T00:00:00Z